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Klf14 Gene Detail
Summary
  • Symbol
    Klf14
  • Name
    Kruppel-like factor 14
  • Synonyms
    5330411L03Rik, BTEB5
  • Feature Type
    protein coding gene
  • IDs
    MGI:3577024
    NCBI Gene: 619665
  • Gene Overview
    MyGene.info: KLF14
Location & Maps
more
  • Sequence Map
    Chr6:30956023-30959078 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3056 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    KLF14, Kruppel-like factor 14
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KLF14, Kruppel-like factor 14
    Orthology source: HomoloGene
  • Synonyms
    BTEB5
  • Links
    NCBI Gene ID: 136259

  • Chr Location
    7q32.3; chr7:130732554-130734033 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Targeted
    2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014454 VEGA Gene Model | MGI Sequence Detail 3056 C57BL/6J ±  kb
transcript OTTMUST00000034294 VEGA | MGI Sequence Detail 3056 Not Applicable  
polypeptide OTTMUSP00000015356 VEGA | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    6 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009358 krueppel-like factor 14
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:2141528
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:214105 de Assuncao TM, et al., New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. J Biol Chem. 2014 May 30;289(22):15798-809

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory