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Ano5
Gene Detail
 Symbol
Name
ID
Ano5
anoctamin 5
MGI:3576659
Synonyms Gdd1, Tmem16e
Feature Type protein coding gene
Genetic Map
Chromosome 7
32.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:51511029-51598709 bp, + strand
From NCBI annotation of GRCm38

  87681 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:100071  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Ano5

Human
homologs
Human Homolog ANO5, anoctamin 5
NCBI Gene ID 203859
neXtProt AC  NX_Q75V66
Human Synonyms  GDD1, LGMD2L, TMEM16E
Human Chr (Location)  11p14.3; chr11:22192667-22283367 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human ANO5
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process biological_process
Component endoplasmic reticulum, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (3)    Images (1)
Theiler Stages: 22, 26, 28
Assay TypeResults
RT-PCR 5
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000055489 (Evidence)
Entrez Gene233246 (Evidence)
DFCITC1591702, TC1592776, TC1594336, TC1626059
DoTSDT.101290340, DT.111003422, DT.91279868, DT.94258834
NIA Mouse Gene IndexU008139
Consensus CDS ProjectCCDS39968.1
International Mouse Knockout Project StatusAno5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 233246 NCBI Gene Model | MGI Sequence Detail 87681 C57BL/6J ±  kb
transcript NM_177694 RefSeq | MGI Sequence Detail 7783 C57BL/6 
polypeptide Q75UR0 UniProt | EBI | MGI Sequence Detail 904 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(13) UniProt(1)
Polymorphisms SNPs within 2kb(769 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007632 Anoctamin/TMEM 16
Protein Ontology PR:000004060 anoctamin-5
Graphical View of Protein Domain Structure
References (Earliest) J:97748 Tsutsumi S, et al., The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet. 2004 Jun;74(6):1255-61
(Latest) J:198369 Suzuki J, et al., Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013 May 10;288(19):13305-16
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory