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Ugt1a8 Gene Detail
Summary
  • Symbol
    Ugt1a8
  • Name
    UDP glucuronosyltransferase 1 family, polypeptide A8
  • Synonyms
    A116, OTTMUSG00000020811
  • Feature Type
    protein coding gene
  • IDs
    MGI:3576090
    NCBI Gene: 613123
  • Member of
    Ugt1 cluster
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88087813-88219004 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 44.50 cM
Strain
Comparison
more
  • SNPs within 2kb
    1242 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3576090
protein coding gene Chr1:88087813-88219004 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016275
protein coding gene Chr1:89483440-89628384 (+)
A/J MGP_AJ_G0016256
protein coding gene Chr1:86144130-86334105 (+)
AKR/J MGP_AKRJ_G0016217
protein coding gene Chr1:88702638-88898486 (+)
BALB/cJ MGP_BALBcJ_G0016213
protein coding gene Chr1:86299311-86472417 (+)
C3H/HeJ MGP_C3HHeJ_G0016041
protein coding gene Chr1:88959274-89122344 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016671
protein coding gene Chr1:92818567-92996661 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014392
protein coding gene Chr1:80649947-80707874 (+)
CAST/EiJ MGP_CASTEiJ_G0015627
protein coding gene Chr1:88168458-88339179 (+)
CBA/J MGP_CBAJ_G0016017
protein coding gene Chr1:95799794-95995698 (+)
DBA/2J MGP_DBA2J_G0016120
protein coding gene Chr1:85426769-85575540 (+)
FVB/NJ MGP_FVBNJ_G0016119
protein coding gene Chr1:84506286-84658652 (+)
LP/J MGP_LPJ_G0016191
protein coding gene Chr1:90530543-90703616 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016145
protein coding gene Chr1:99042603-99344403 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016713
protein coding gene Chr1:88790422-88953955 (+)
PWK/PhJ MGP_PWKPhJ_G0015413
protein coding gene Chr1:84774315-84935769 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015193
protein coding gene Chr1:87726363-87876024 (+)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089675 Ensembl Gene Model | MGI Sequence Detail 131192 C57BL/6J ±  kb
transcript ENSMUST00000113139 Ensembl | MGI Sequence Detail 2227 Not Applicable  
polypeptide ENSMUSP00000108764 Ensembl | MGI Sequence Detail 530 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1
Other
Accession IDs
less
MGI:3707579
References
more
  • Summaries
    All 14
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory