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Ugt1a2
Gene Detail
Symbol

Name
ID
Member of
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
MGI:3576049
Ugt1 cluster
Feature Type
protein coding gene
Genetic Map
Chromosome 1
44.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:88200601-88218997 bp, + strand
From VEGA annotation of GRCm38

  18397 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:86211  Vertebrate Homology Class
1 human; 1 mouse; 1 rat

HCOP human homology predictions: UGT1A3
Protein SuperFamily: glucuronosyltransferase
Gene Tree: Ugt1a2

Human
homologs
UGT1A3, UDP glucuronosyltransferase 1 family, polypeptide A3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 54659
neXtProt AC: NX_P35503

Human Synonyms: UDPGT, UDPGT 1-3, UGT1-03, UGT1.3, UGT1A3S, UGT1C, UGT-1C

Human Chr (Location): 2q37; chr2:233729127-233773299 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ugt1a2 interacts with 140 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cellular glucuronidation, cellular response to hormone stimulus, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function enzyme binding, glucuronosyltransferase activity, ...
External Resources: FuncBase
Expression
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(1) cDNA(5)
Other database
links
VEGA Gene Model OTTMUSG00000020805 (Evidence)
Ensembl Gene Model ENSMUSG00000090171 (Evidence)
Entrez Gene 22236 (Evidence)
DFCI TC1580878
DoTS DT.537397
EC 2.4.1.17
Consensus CDS Project CCDS15141.1
International Mouse Phenotyping Consortium Status Ugt1a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020805 VEGA Gene Model | MGI Sequence Detail 18397 C57BL/6J ±  kb
transcript OTTMUST00000049207 VEGA | MGI Sequence Detail 2211 Not Applicable 
polypeptide OTTMUSP00000022760 VEGA | MGI Sequence Detail 533 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(243 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
Protein Ontology PR:000017222 UDP-glucuronosyltransferase 1-2
References
(Earliest) J:25115 Koiwai O, et al., Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations. Biochem Genet. 1995 Apr;33(3-4):111-22
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(19)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory