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Ear14 Gene Detail
Summary
  • Symbol
    Ear14
  • Name
    eosinophil-associated, ribonuclease A family, member 14
  • Feature Type
    protein coding gene
  • IDs
    MGI:3528616
    NCBI Gene: 503847
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:51203695-51204156 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.42 cM, cytoband B-C1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3528616
protein coding gene Chr14:51203391-51204338 (.)
129S1/SvImJ no annotation
A/J MGP_AJ_G0021232
protein coding gene Chr14:43825366-43825928 (+)
AKR/J MGP_AKRJ_G0021208
protein coding gene Chr14:45506755-45507257 (+)
BALB/cJ MGP_BALBcJ_G0021235
protein coding gene Chr14:43986518-43987080 (+)
C3H/HeJ MGP_C3HHeJ_G0021017
protein coding gene Chr14:45314781-45315393 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021672
protein coding gene Chr14:47046148-47046615 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0021108
protein coding gene Chr14:43710758-43711260 (+)
FVB/NJ MGP_FVBNJ_G0021087
protein coding gene Chr14:43350177-43350789 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0021115
protein coding gene Chr14:48006684-48007296 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021701
protein coding gene Chr14:44952219-44952686 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0020114
protein coding gene Chr14:41132942-41133343 (+)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 503847 NCBI Gene Model | MGI Sequence Detail 462 C57BL/6J ±  kb
transcript NM_017389 RefSeq | MGI Sequence Detail 462 C57BL/6  
polypeptide NP_059085 RefSeq | MGI Sequence Detail 153 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001427 Pancreatic ribonuclease
    IPR023411 Ribonuclease A, active site
    IPR023412 Ribonuclease A-domain
    IPR036816 Ribonuclease A-like domain superfamily
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 15
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:69087 Cormier SA, et al., Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis. Mamm Genome. 2001 May;12(5):352-61
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory