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Rnase12
Gene Detail
 Symbol
Name
ID
Rnase12
ribonuclease, RNase A family, 12 (non-active)
MGI:3528588
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.36 cM, cytoband B-C1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:51056783-51057220 bp, - strand
From NCBI annotation of GRCm38

  438 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84641  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase12

Human
homologs
Human Homolog RNASE12, ribonuclease, RNase A family, 12 (non-active)
NCBI Gene ID 493901
neXtProt AC  NX_Q5GAN4
Human Synonyms  HEL-S-85p, RAI1
Human Chr (Location)  14q11.1; chr14:20590080-20590823 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component extracellular region
Function nucleic acid binding
External Resources: FuncBase
Expression
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000068407 (Evidence)
Entrez Gene497106 (Evidence)
UniGene379740
DoTSDT.110754138
Consensus CDS ProjectCCDS27032.1
International Mouse Knockout Project StatusRnase12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 497106 NCBI Gene Model | MGI Sequence Detail 438 C57BL/6J ±  kb
transcript NM_001011875 RefSeq | MGI Sequence Detail 545 Not Specified 
polypeptide Q5GAM8 UniProt | EBI | MGI Sequence Detail 145 Not Applicable 

For the selected sequences
All sequences(12) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023412 Ribonuclease A-domain
Protein Ontology PR:000014044 ribonuclease-like protein 12
Graphical View of Protein Domain Structure
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(19)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory