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Rnase12 Gene Detail
Summary
  • Symbol
    Rnase12
  • Name
    ribonuclease, RNase A family, 12 (non-active)
  • Feature Type
    protein coding gene
  • IDs
    MGI:3528588
    NCBI Gene: 497106
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:51056698-51057242 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.36 cM, cytoband B-C1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3528588
protein coding gene Chr14:51056698-51057661 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021269
protein coding gene Chr14:45006172-45006716 (-)
A/J MGP_AJ_G0021223
protein coding gene Chr14:43658198-43658742 (-)
AKR/J MGP_AKRJ_G0021199
protein coding gene Chr14:45306946-45307490 (-)
BALB/cJ MGP_BALBcJ_G0021226
protein coding gene Chr14:43782086-43782630 (-)
C3H/HeJ MGP_C3HHeJ_G0021008
protein coding gene Chr14:45131160-45131704 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021663
protein coding gene Chr14:46869149-46869693 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019215
protein coding gene Chr14:42993386-42993930 (-)
CAST/EiJ MGP_CASTEiJ_G0020532
protein coding gene Chr14:42204553-42205097 (-)
CBA/J MGP_CBAJ_G0020975
protein coding gene Chr14:48321442-48321986 (-)
DBA/2J MGP_DBA2J_G0021099
protein coding gene Chr14:43552516-43553060 (-)
FVB/NJ MGP_FVBNJ_G0021080
protein coding gene Chr14:43179387-43179931 (-)
LP/J MGP_LPJ_G0021167
protein coding gene Chr14:45297776-45298320 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021108
protein coding gene Chr14:47813613-47814157 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021692
protein coding gene Chr14:44789096-44789640 (-)
PWK/PhJ MGP_PWKPhJ_G0020282
protein coding gene Chr14:40456053-40456597 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020107
protein coding gene Chr14:40963577-40964121 (-)
WSB/EiJ MGP_WSBEiJ_G0020585
protein coding gene Chr14:44993362-44993906 (-)



Homology
more
  • Human Ortholog
    RNASE12, ribonuclease A family member 12 (inactive)
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RNASE12, ribonuclease A family member 12 (inactive)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEL-S-85p, RAI1
  • Links
    NCBI Gene ID: 493901
    neXtProt AC: NX_Q5GAN4
    UniProt: Q5GAN4

  • Chr Location
    14q11.2; chr14:20590080-20590823 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 497106 NCBI Gene Model | MGI Sequence Detail 545 C57BL/6J ±  kb
transcript NM_001011875 RefSeq | MGI Sequence Detail 545 Not Specified  
polypeptide Q5GAM8 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory