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Gpr62 Gene Detail
Summary
  • Symbol
    Gpr62
  • Name
    G protein-coupled receptor 62
  • Synonyms
    4933402E03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3525078
    NCBI Gene: 436090
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:106341161-106343137 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 57.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3525078
 protein coding gene Chr9:106341161-106343184 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035233
 protein coding gene Chr9:108273725-108275702 (-)
A/J MGP_AJ_G0035212
 protein coding gene Chr9:104360272-104362249 (-)
AKR/J MGP_AKRJ_G0035144
 protein coding gene Chr9:106961013-106962990 (-)
BALB/cJ MGP_BALBcJ_G0035206
 protein coding gene Chr9:104045864-104047841 (-)
C3H/HeJ MGP_C3HHeJ_G0034916
 protein coding gene Chr9:107375340-107377317 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035726
 protein coding gene Chr9:111258364-111260340 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032624
 protein coding gene Chr9:101850732-101852692 (-)
CAST/EiJ MGP_CASTEiJ_G0034227
 protein coding gene Chr9:107279547-107281523 (-)
CBA/J MGP_CBAJ_G0034884
 protein coding gene Chr9:115192922-115194898 (-)
DBA/2J MGP_DBA2J_G0035045
 protein coding gene Chr9:103822992-103824969 (-)
FVB/NJ MGP_FVBNJ_G0034993
 protein coding gene Chr9:102602109-102604086 (-)
LP/J MGP_LPJ_G0035121
 protein coding gene Chr9:108495516-108497493 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035032
 protein coding gene Chr9:116784733-116786710 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035747
 protein coding gene Chr9:107207306-107209283 (-)
PWK/PhJ MGP_PWKPhJ_G0033934
 protein coding gene Chr9:104121715-104123691 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033769
 protein coding gene Chr9:107278615-107280591 (-)
WSB/EiJ MGP_WSBEiJ_G0034348
 protein coding gene Chr9:107106329-107108306 (-)



Homology
more
  • Human Ortholog
    GPR62, G protein-coupled receptor 62
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR62, G protein-coupled receptor 62
  • Synonyms
    GPCR8, KPG_005
  • Links
    NCBI Gene ID: 118442
    neXtProt AC: NX_Q9BZJ7
    UniProt: Q9BZJ7

  • Chr Location
    3p21.2; chr3:51955381-51957499 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a knock-out allele are viable and show normal growth, behavior and fertility in both sexes, with no detectable alterations in sperm differentiation, count or motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091735 Ensembl Gene Model | MGI Sequence Detail 1977 C57BL/6J ±  kb
transcript ENSMUST00000164834 Ensembl | MGI Sequence Detail 1977 Not Applicable  
polypeptide ENSMUSP00000129055 Ensembl | MGI Sequence Detail 358 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:1914001
References
more
  • Summaries
    All 25
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:253644 Muroi T, et al., GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice. Reproduction. 2017 Dec;154(6):755-764
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory