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Csta1 Gene Detail
Summary
  • Symbol
    Csta1
  • Name
    cystatin A1
  • Synonyms
    Csta
  • Feature Type
    protein coding gene
  • IDs
    MGI:3524930
    NCBI Gene: 209294
  • Gene Overview
    MyGene.info: CSTA
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:36119946-36131189 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    62 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3524930
protein coding gene Chr16:36119946-36131241 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022779
protein coding gene Chr16:34492212-34503474 (-)
A/J MGP_AJ_G0022744
protein coding gene Chr16:32814196-32825487 (-)
AKR/J MGP_AKRJ_G0022717
protein coding gene Chr16:33968262-33983881 (-)
BALB/cJ MGP_BALBcJ_G0022746
protein coding gene Chr16:32937249-32949997 (-)
C3H/HeJ MGP_C3HHeJ_G0022511
protein coding gene Chr16:34093124-34104917 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023195
protein coding gene Chr16:35228741-35240865 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020713
protein coding gene Chr16:33162203-33173724 (-)
CAST/EiJ MGP_CASTEiJ_G0022039
protein coding gene Chr16:34321596-34333323 (-)
CBA/J MGP_CBAJ_G0022481
protein coding gene Chr16:36681045-36695520 (-)
DBA/2J MGP_DBA2J_G0022614
protein coding gene Chr16:32640621-32652955 (-)
FVB/NJ MGP_FVBNJ_G0022589
protein coding gene Chr16:32633416-32644662 (-)
LP/J MGP_LPJ_G0022681
protein coding gene Chr16:34217468-34229707 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022608
protein coding gene Chr16:35935563-35948646 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023207
protein coding gene Chr16:34028543-34039800 (-)
PWK/PhJ MGP_PWKPhJ_G0021780
protein coding gene Chr16:33057324-33073334 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021611
protein coding gene Chr16:33830385-33844757 (-)
WSB/EiJ MGP_WSBEiJ_G0022083
protein coding gene Chr16:33948489-33959563 (-)



Homology
more
  • Human Ortholog
    CSTA, cystatin A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CSTA, cystatin A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AREI, PSS4, STF1, STFA
  • Links
    NCBI Gene ID: 1475
    neXtProt AC: NX_P01040
    UniProt: P01040

  • Chr Location
    3q21.1; chr3:122325164-122341969 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 209294 NCBI Gene Model | MGI Sequence Detail 11244 C57BL/6J ±  kb
transcript NM_001033239 RefSeq | MGI Sequence Detail 2731 C57BL/6  
polypeptide P56567 UniProt | EBI | MGI Sequence Detail 97 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000010 Cystatin domain
    IPR001713 Proteinase inhibitor I25A, stefin
    IPR018073 Proteinase inhibitor I25, cystatin, conserved site
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:47659 Sasaki N, et al., Characterization of gene expression in mouse blastocyst using single-pass sequencing of 3995 clones. (Errata 1998;54:583). Genomics. 1998 Apr 15;49(2):167-79
  • Latest
    J:229630 Gupta A, et al., Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion. PLoS One. 2015;10(3):e0120091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory