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Tmprss11c Gene Detail
Summary
  • Symbol
    Tmprss11c
  • Name
    transmembrane protease, serine 11c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3521861
    NCBI Gene: 435845
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr5:86379340-86437167 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    378 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3521861
 protein coding gene Chr5:86376600-86437167 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029667
 protein coding gene Chr5:87065834-87130981 (-)
A/J MGP_AJ_G0029635
 protein coding gene Chr5:83499047-83561682 (-)
AKR/J MGP_AKRJ_G0029583
 protein coding gene Chr5:86274250-86334371 (-)
BALB/cJ MGP_BALBcJ_G0029644
 protein coding gene Chr5:84405311-84469938 (-)
C3H/HeJ MGP_C3HHeJ_G0029367
 protein coding gene Chr5:86758618-86822863 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030098
 protein coding gene Chr5:90653181-90721194 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027340
 protein coding gene Chr5:79345847-79401555 (-)
CAST/EiJ MGP_CASTEiJ_G0028775
 protein coding gene Chr5:86025644-86097172 (-)
CBA/J MGP_CBAJ_G0029336
 protein coding gene Chr5:93566528-93627035 (-)
DBA/2J MGP_DBA2J_G0029481
 protein coding gene Chr5:83705200-83763152 (-)
FVB/NJ MGP_FVBNJ_G0029442
 protein coding gene Chr5:82626320-82684006 (-)
LP/J MGP_LPJ_G0029568
 protein coding gene Chr5:87468291-87528902 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029470
 protein coding gene Chr5:98404624-98476112 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030131
 protein coding gene Chr5:85852019-85911299 (-)
PWK/PhJ MGP_PWKPhJ_G0028499
 protein coding gene Chr5:82657943-82727087 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028333
 protein coding gene Chr5:85218281-85283197 (-)
WSB/EiJ MGP_WSBEiJ_G0028856
 protein coding gene Chr5:86201867-86266424 (-)



Homology
more
  • Human Ortholog
    TMPRSS11CP, transmembrane serine protease 11C, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMPRSS11CP, transmembrane serine protease 11C, pseudogene
  • Links
    NCBI Gene ID: 100381178

  • Chr Location
    chr4:67765914-67774454 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    11 phenotype references
Mice homozygous for a null allele in combination with other Tmprss11 null alleles are normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061184 Ensembl Gene Model | MGI Sequence Detail 57828 C57BL/6J ±  kb
transcript ENSMUST00000059424 Ensembl | MGI Sequence Detail 1615 Not Applicable  
polypeptide ENSMUSP00000062915 Ensembl | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:279596 Callies LK, et al., Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters. J Biol Chem. 2019 Sep 9;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory