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Kcnk9
Gene Detail
 Symbol
Name
ID
Kcnk9
potassium channel, subfamily K, member 9
MGI:3521816
Synonyms Task3
Feature Type protein coding gene
Genetic Map
Chromosome 15
33.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:72512119-72546279 bp, - strand
From NCBI annotation of GRCm38

  34161 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56758  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: potassium channel, subfamily K type
Gene Tree: Kcnk9

Human
homologs
Human Homolog KCNK9, potassium channel, subfamily K, member 9
NCBI Gene ID 51305
neXtProt AC  NX_Q9NPC2
Human Synonyms  K2p9.1, KT3.2, TASK3, TASK-3
Human Chr (Location)  8q24.3; chr8:139600838-139703056 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human KCNK9
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Radiation induced(1) Targeted(9)
Genomic Mutations involving Kcnk9 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit decreased pH sensitive action potential in serotonergic neurons.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function potassium channel activity, protein heterodimerization activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (7)   
Theiler Stages: 2, 3, 4, 28
Assay TypeResults
Immunohistochemistry 3
RT-PCR 10
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(2) Primer pair(2)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000036760 (Evidence)
Entrez Gene223604 (Evidence)
UniGene386856
DoTSDT.110789637
NIA Mouse Gene IndexU090668
Consensus CDS ProjectCCDS27515.1
International Mouse Knockout Project StatusKcnk9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 223604 NCBI Gene Model | MGI Sequence Detail 34161 C57BL/6J ±  kb
transcript NM_001033876 RefSeq | MGI Sequence Detail 1209 NMRI 
polypeptide Q3LS21 UniProt | EBI | MGI Sequence Detail 402 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013099 Ion transport 2
InterPro IPR003280 Two pore domain potassium channel
InterPro IPR005407 Two pore domain potassium channel, TASK-3
InterPro IPR003092 Two pore domain potassium channel, TASK family
Protein Ontology PR:000002079 potassium channel subfamily K member 9
Graphical View of Protein Domain Structure
References (Earliest) J:124944 Brickley SG, et al., TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. J Neurosci. 2007 Aug 29;27(35):9329-40
(Latest) J:201183 Bandulik S, et al., Severe hyperaldosteronism in neonatal Task3 potassium channel knockout mice is associated with activation of the intraadrenal renin-angiotensin system. Endocrinology. 2013 Aug;154(8):2712-22
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/02/2014
MGI 5.19
The Jackson Laboratory