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Apcdd1
Gene Detail
Symbol

Name
ID
Apcdd1
adenomatosis polyposis coli down-regulated 1
MGI:3513977
Synonyms
Drapc1, EIG180
Feature Type
protein coding gene
Genetic Map
Chromosome 18
35.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:62922327-62953195 bp, + strand
From NCBI annotation of GRCm38

  30869 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77420  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: APCDD1
Gene Tree: Apcdd1

Human
homologs
APCDD1, adenomatosis polyposis coli down-regulated 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 147495
neXtProt AC: NX_Q8J025

Human Synonyms: B7323, DRAPC1, FP7019, HHS, HTS, HYPT1

Human Chr (Location): 18p11.22; chr18:10454628-10488701 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human APCDD1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Apcdd1 interacts with 178 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process astrocyte cell migration, hair follicle development, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function Wnt-protein binding
External Resources: FuncBase
Expression
Literature Summary: (18 records)
Data Summary: Results (166)    Tissues (107)    Images (45)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 164
RT-PCR 2
cDNA source data(56)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: GEISHA APCDD1 ; Xenbase apcdd1    NEW 
Molecular
reagents
All nucleic(59) cDNA(56) Primer pair(2) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000071847 (Evidence)
Entrez Gene 494504 (Evidence)
UniGene 391102
DoTS DT.110750103, DT.532024, DT.110750120, DT.110750145
NIA Mouse Gene Index U300011, U018806
Consensus CDS Project CCDS37843.1
International Mouse Phenotyping Consortium Status Apcdd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 494504 NCBI Gene Model | MGI Sequence Detail 30869 C57BL/6J ±  kb
transcript NM_133237 RefSeq | MGI Sequence Detail 2799 NOD 
polypeptide Q3U128 UniProt | EBI | MGI Sequence Detail 514 Not Applicable 

For the selected sequences
All sequences(115) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000004124 protein APCDD1
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:216214 Raspopovic J, et al., Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients. Science. 2014 Aug 1;345(6196):566-70
All references(43)
Other
accession IDs
MGI:2147323, MGI:2181620

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory