Apcdd1
Gene Detail

Symbol Name ID

Apcdd1 adenomatosis polyposis coli down-regulated 1 MGI:3513977

Synonyms

Drapc1, EIG180

Feature Type

protein coding gene

Genetic Map

Chromosome 18

35.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr18:62922327-62953195 bp, + strand From NCBI annotation of GRCm38   30869 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:77420  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Apcdd1

Human homologs

Human Homolog		APCDD1, adenomatosis polyposis coli down-regulated 1
NCBI Gene ID		147495
neXtProt AC		NX_Q8J025
Human Synonyms		B7323, DRAPC1, HHS, HTS
Human Chr (Location)		18p11.22; chr18:10454625-10488698 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human APCDD1

Alleles and phenotypes

All alleles(4) : Targeted(4)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	astrocyte cell migration, hair follicle development, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	Wnt-protein binding

External Resources: FuncBase

Expression

Literature Summary: (13 records)
Data Summary: Results (156)    Tissues (106)    Images (41)
Theiler Stages: 11, 12, 13, 15, 17, 19, 21, 22, 23, 28

Assay Type	Results
RNA in situ	154
RT-PCR	2

cDNA source data(58)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(60) cDNA(58) Primer pair(2)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000071847 (Evidence)
Entrez Gene	494504 (Evidence)
UniGene	391102
DoTS	DT.110750103, DT.110750120, DT.110750145, DT.532024
NIA Mouse Gene Index	U018806, U300011
Consensus CDS Project	CCDS37843.1
International Mouse Knockout Project Status	Apcdd1

Sequences

Length	Strain/Species
genomic	494504	NCBI Gene Model | MGI Sequence Detail	30869	C57BL/6J
transcript	NM_133237	RefSeq | MGI Sequence Detail	2799	NOD
polypeptide	Q3U128	UniProt | EBI | MGI Sequence Detail	514	Not Applicable

All sequences(77) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(94 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000004124	protein APCDD1

Graphical View of Protein Domain Structure

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:188394 Kang P, et al., Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron. 2012 Apr 12;74(1):79-94
All references(39)

Other accession IDs

MGI:2147323, MGI:2181620