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Apcdd1 Gene Detail
Summary
  • Symbol
    Apcdd1
  • Name
    adenomatosis polyposis coli down-regulated 1
  • Synonyms
    Drapc1, EIG180
  • Feature Type
    protein coding gene
  • IDs
    MGI:3513977
    NCBI Gene: 494504
Location & Maps
more
  • Sequence Map
    Chr18:62922327-62953195 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30869 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 35.95 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    APCDD1, adenomatosis polyposis coli down-regulated 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    APCDD1, adenomatosis polyposis coli down-regulated 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B7323, DRAPC1, FP7019, HHS, HTS, HYPT1
  • Links
    NCBI Gene ID: 147495
    neXtProt AC: NX_Q8J025

  • Chr Location
    18p11.22; chr18:10454628-10488701 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human APCDD1 associations

Human Disease Mouse Models
       Hypotrichosis 1; HYPT1   OMIM: 605389
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 494504 NCBI Gene Model | MGI Sequence Detail 30869 C57BL/6J ±  kb
transcript NM_133237 RefSeq | MGI Sequence Detail 2799 NOD  
polypeptide Q3U128 UniProt | EBI | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    109 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 56
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147323, MGI:2181620
References
more
  • Summaries
    All 42
    Developmental Gene Expression 19
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:223938 Lee HK, et al., Apcdd1 stimulates oligodendrocyte differentiation after white matter injury. Glia. 2015 Oct;63(10):1840-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory