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Apcdd1
Gene Detail
 Symbol
Name
ID
Apcdd1
adenomatosis polyposis coli down-regulated 1
MGI:3513977
Synonyms Drapc1, EIG180
Feature Type protein coding gene
Genetic Map
Chromosome 18
35.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:62922327-62953195 bp, + strand
From NCBI annotation of GRCm38

  30869 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77420  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Apcdd1

Human
homologs
Human Homolog APCDD1, adenomatosis polyposis coli down-regulated 1
NCBI Gene ID 147495
neXtProt AC  NX_Q8J025
Human Synonyms  B7323, DRAPC1, HHS, HTS, HYPT1
Human Chr (Location)  18p11.22; chr18:10454628-10488701 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human APCDD1
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Apcdd1 interacts with 179 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process astrocyte cell migration, hair follicle development, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function Wnt-protein binding
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (166)    Tissues (107)    Images (45)
Theiler Stages: 11, 12, 13, 14, 15, 17, 19, 21, 22, 23, 28
Assay TypeResults
RNA in situ 164
RT-PCR 2
cDNA source data(56)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(59) cDNA(56) Primer pair(2) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000071847 (Evidence)
Entrez Gene494504 (Evidence)
UniGene391102
DoTSDT.110750103, DT.110750120, DT.110750145, DT.532024
NIA Mouse Gene IndexU018806, U300011
Consensus CDS ProjectCCDS37843.1
International Mouse Knockout Project StatusApcdd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 494504 NCBI Gene Model | MGI Sequence Detail 30869 C57BL/6J ±  kb
transcript NM_133237 RefSeq | MGI Sequence Detail 2799 NOD 
polypeptide Q3U128 UniProt | EBI | MGI Sequence Detail 514 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000004124 protein APCDD1
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:199302 Veenvliet JV, et al., Specification of dopaminergic subsets involves interplay of En1 and Pitx3. Development. 2013 Aug;140(16):3373-84
All references(42)
Other
accession IDs
MGI:2147323, MGI:2181620

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory