About   Help   FAQ
Nt5dc3 Gene Detail
Summary
  • Symbol
    Nt5dc3
  • Name
    5'-nucleotidase domain containing 3
  • Synonyms
    C630002B14Rik, Gnn
  • Feature Type
    protein coding gene
  • IDs
    MGI:3513266
    NCBI Gene: 103466
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:86614869-86674253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 43.11 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    284 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3513266
 protein coding gene Chr10:86614857-86674253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017615
 protein coding gene Chr10:87764563-87819050 (+)
A/J MGP_AJ_G0017594
 protein coding gene Chr10:84860885-84913564 (+)
AKR/J MGP_AKRJ_G0017552
 protein coding gene Chr10:87242728-87301861 (+)
BALB/cJ MGP_BALBcJ_G0017557
 protein coding gene Chr10:85123273-85176330 (+)
C3H/HeJ MGP_C3HHeJ_G0017380
 protein coding gene Chr10:87243935-87297345 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018014
 protein coding gene Chr10:90734257-90793302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015696
 protein coding gene Chr10:80660630-80715663 (+)
CAST/EiJ MGP_CASTEiJ_G0016945
 protein coding gene Chr10:87134629-87192218 (+)
CBA/J MGP_CBAJ_G0017349
 protein coding gene Chr10:94502414-94563326 (+)
DBA/2J MGP_DBA2J_G0017455
 protein coding gene Chr10:83963139-84017473 (+)
FVB/NJ MGP_FVBNJ_G0017447
 protein coding gene Chr10:83227397-83288938 (+)
LP/J MGP_LPJ_G0017529
 protein coding gene Chr10:88458684-88514902 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017478
 protein coding gene Chr10:96075536-96129759 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018051
 protein coding gene Chr10:87093013-87145910 (+)
PWK/PhJ MGP_PWKPhJ_G0016726
 protein coding gene Chr10:83970468-84031225 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016514
 protein coding gene Chr10:85815702-85873618 (+)
WSB/EiJ MGP_WSBEiJ_G0017004
 protein coding gene Chr10:87050687-87112221 (+)



Homology
more
  • Human Ortholog
    NT5DC3, 5'-nucleotidase domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NT5DC3, 5'-nucleotidase domain containing 3
  • Synonyms
    TU12B1TY, TU12B1-TY
  • Links
    NCBI Gene ID: 51559
    neXtProt AC: NX_Q86UY8
    UniProt: Q86UY8

  • Chr Location
    12q23.3; chr12:103746315-103841238 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    687
  • Tissues
    15
  • cDNA Data
    35
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054027 Ensembl Gene Model | MGI Sequence Detail 59385 C57BL/6J ±  kb
transcript ENSMUST00000099396 Ensembl | MGI Sequence Detail 5952 Not Applicable  
polypeptide ENSMUSP00000096994 Ensembl | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143753, MGI:2143852
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
06/23/2022
MGI 6.20 		The Jackson Laboratory