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Tmprss11e Gene Detail
Summary
  • Symbol
    Tmprss11e
  • Name
    transmembrane protease, serine 11e
  • Synonyms
    DESC1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3513175
    NCBI Gene: 243084
Location & Maps
more
  • Sequence Map
    Chr5:86705186-86745815 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40630 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 43.56 cM, cytoband E1
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMPRSS11E, transmembrane protease, serine 11E
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMPRSS11E, transmembrane protease, serine 11E
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DESC1, TMPRSS11E2
  • Links
    NCBI Gene ID: 28983
    neXtProt AC: NX_Q9UL52

  • Chr Location
    4q13.2; chr4:68447449-68497604 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    6
  • Genomic Mutations
    4 involving Tmprss11e
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035105 VEGA Gene Model | MGI Sequence Detail 40630 C57BL/6J ±  kb
transcript OTTMUST00000089305 VEGA | MGI Sequence Detail 3416 Not Applicable  
polypeptide OTTMUSP00000048794 VEGA | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    330 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:94483 Hobson JP, et al., Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes. J Biol Chem. 2004 Nov 5;279(45):46981-94
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory