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Cbx6
Gene Detail
Symbol

Name
ID
Cbx6
chromobox 6
MGI:3512628
Feature Type
protein coding gene
Genetic Map
Chromosome 15
37.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:79823896-79834688 bp, - strand
From VEGA annotation of GRCm38

  10793 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8619  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CBX6
Gene Tree: Cbx6

Human
homologs
CBX6, chromobox homolog 6
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23466
neXtProt AC: NX_O95503

Human Chr (Location): 22q13.1; chr22:38861216-38872334 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Radiation induced(1) Targeted(4)
Genomic Mutations involving Cbx6 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Cbx6 interacts with 344 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process chromatin modification, negative regulation of transcription from RNA polymerase II promoter, ...
Component heterochromatin, nucleus, ...
Function single-stranded RNA binding
External Resources: FuncBase
Expression
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cbx6 ; ZFIN cbx6a    NEW 
Molecular
reagents
All nucleic(16) Genomic(1) cDNA(15)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000017454 (Evidence)
Ensembl Gene Model ENSMUSG00000089715 (Evidence)
Entrez Gene 494448 (Evidence)
DFCI TC1573968, TC1579596, TC1774200
DoTS DT.110807565, DT.40167491, DT.94308697, DT.94368947, DT.97342282, DT.97405219, DT.99854877, DT.99866238
Consensus CDS Project CCDS37142.1
International Mouse Phenotyping Consortium Status Cbx6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017454 VEGA Gene Model | MGI Sequence Detail 10793 C57BL/6J ±  kb
transcript OTTMUST00000042382 VEGA | MGI Sequence Detail 5806 Not Applicable 
polypeptide OTTMUSP00000019047 VEGA | MGI Sequence Detail 414 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000953 Chromo/chromo shadow domain
InterPro IPR023780 Chromo domain
InterPro IPR023779 Chromo domain, conserved site
InterPro IPR016197 Chromo domain-like
InterPro IPR017984 Chromo domain subgroup
Protein Ontology PR:000005087 chromobox protein homolog 6
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:209956 Liakath-Ali K, et al., Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Nat Commun. 2014;5:3540
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory