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Fcho2 Gene Detail
Summary
  • Symbol
    Fcho2
  • Name
    FCH domain only 2
  • Synonyms
    5832424M12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3505790
    NCBI Gene: 218503
  • Gene Overview
    MyGene.info: FCHO2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:98723403-98815449 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 52.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    248 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3505790
protein coding gene Chr13:98723403-98815768 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020870
protein coding gene Chr13:100461131-100567200 (-)
A/J MGP_AJ_G0020824
protein coding gene Chr13:96632496-96725425 (-)
AKR/J MGP_AKRJ_G0020798
protein coding gene Chr13:99578772-99676745 (-)
BALB/cJ MGP_BALBcJ_G0020822
protein coding gene Chr13:97339034-97431417 (-)
C3H/HeJ MGP_C3HHeJ_G0020613
protein coding gene Chr13:99323165-99422883 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021256
protein coding gene Chr13:103469695-103571986 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018825
protein coding gene Chr13:92363720-92458583 (-)
CAST/EiJ MGP_CASTEiJ_G0020131
protein coding gene Chr13:98683441-98796115 (-)
CBA/J MGP_CBAJ_G0020573
protein coding gene Chr13:107586687-107703132 (-)
DBA/2J MGP_DBA2J_G0020698
protein coding gene Chr13:96397966-96490926 (-)
FVB/NJ MGP_FVBNJ_G0020679
protein coding gene Chr13:95147329-95242949 (-)
LP/J MGP_LPJ_G0020773
protein coding gene Chr13:100567244-100667929 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020707
protein coding gene Chr13:107915256-108023933 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021297
protein coding gene Chr13:99026021-99124237 (-)
PWK/PhJ MGP_PWKPhJ_G0019884
protein coding gene Chr13:95205860-95303764 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019707
protein coding gene Chr13:95334037-95432837 (-)
WSB/EiJ MGP_WSBEiJ_G0020189
protein coding gene Chr13:99473441-99572154 (-)



Homology
more
  • Human Ortholog
    FCHO2, FCH domain only 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FCHO2, FCH domain only 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 115548
    neXtProt AC: NX_Q0JRZ9
    UniProt: Q0JRZ9

  • Chr Location
    5q13.2; chr5:72955981-73090522 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9030
    1 human;1 mouse;1 rat;1 chimpanzee;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FCHO2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041685 Ensembl Gene Model | MGI Sequence Detail 92047 C57BL/6J ±  kb
transcript ENSMUST00000040340 Ensembl | MGI Sequence Detail 5122 Not Applicable  
polypeptide ENSMUSP00000042959 Ensembl | MGI Sequence Detail 809 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 98
    cDNA 98

    Microarray probesets 4
Other
Accession IDs
less
MGI:3035164
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:185432 Umasankar PK, et al., Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol. 2012 May;14(5):488-501

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory