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Spag8 Gene Detail
Summary
  • Symbol
    Spag8
  • Name
    sperm associated antigen 8
  • Feature Type
    protein coding gene
  • IDs
    MGI:3056295
    NCBI Gene: 433700
  • Gene Overview
    MyGene.info: SPAG8
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:43651335-43653594 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 23.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    59 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3056295
protein coding gene Chr4:43651330-43654132 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028218
protein coding gene Chr4:41784563-41786822 (-)
A/J MGP_AJ_G0028174
protein coding gene Chr4:40295271-40297530 (-)
AKR/J MGP_AKRJ_G0028126
protein coding gene Chr4:41207503-41209762 (-)
BALB/cJ MGP_BALBcJ_G0028194
protein coding gene Chr4:40385426-40387685 (-)
C3H/HeJ MGP_C3HHeJ_G0027916
protein coding gene Chr4:41845204-41847463 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028635
protein coding gene Chr4:43345300-43347559 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025947
protein coding gene Chr4:37742678-37744956 (-)
CAST/EiJ MGP_CASTEiJ_G0027356
protein coding gene Chr4:41352099-41354357 (-)
CBA/J MGP_CBAJ_G0027882
protein coding gene Chr4:44671384-44673643 (-)
DBA/2J MGP_DBA2J_G0028031
protein coding gene Chr4:40205810-40208069 (-)
FVB/NJ MGP_FVBNJ_G0027998
protein coding gene Chr4:39432303-39434562 (-)
LP/J MGP_LPJ_G0028130
protein coding gene Chr4:41836011-41838270 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028022
protein coding gene Chr4:47922672-47924931 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028671
protein coding gene Chr4:41418148-41420407 (-)
PWK/PhJ MGP_PWKPhJ_G0027082
protein coding gene Chr4:40241476-40243734 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026908
protein coding gene Chr4:40984990-40987253 (-)
WSB/EiJ MGP_WSBEiJ_G0027436
protein coding gene Chr4:41315893-41318152 (-)



Homology
more
  • Human Ortholog
    SPAG8, sperm associated antigen 8
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SPAG8, sperm associated antigen 8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BS-84, CILD28, CT142, HSD-1, hSMP-1, SMP1, SPAG3
  • Links
    NCBI Gene ID: 26206
    neXtProt AC: NX_Q99932
    UniProt: Q99932

  • Chr Location
    9p13.3; chr9:35807785-35812262 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically and radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Spag8
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066196 Ensembl Gene Model | MGI Sequence Detail 2260 C57BL/6J ±  kb
transcript ENSMUST00000084646 Ensembl | MGI Sequence Detail 1549 Not Applicable  
polypeptide ENSMUSP00000081696 Ensembl | MGI Sequence Detail 470 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory