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Ano7 Gene Detail
Summary
  • Symbol
    Ano7
  • Name
    anoctamin 7
  • Synonyms
    IPCA-5, NGEP, NGEP-L, Pcanap5, Tmem16g
  • Feature Type
    protein coding gene
  • IDs
    MGI:3052714
    NCBI Gene: 404545
Location & Maps
more
  • Sequence Map
    Chr1:93373930-93404303 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30374 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 47.24 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ANO7, anoctamin 7
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ANO7, anoctamin 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DTMPP, D-TMPP, IPCA5, IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G
  • Links
    NCBI Gene ID: 50636
    neXtProt AC: NX_Q6IWH7

  • Chr Location
    2q37.3; chr2:241188509-241239595 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Ano7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048653 VEGA Gene Model | MGI Sequence Detail 30374 C57BL/6J ±  kb
transcript OTTMUST00000124598 VEGA | MGI Sequence Detail 3984 Not Applicable  
polypeptide OTTMUSP00000067766 VEGA | MGI Sequence Detail 859 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    230 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:88660 Bera TK, et al., NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3059-64
  • Latest
    J:198369 Suzuki J, et al., Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013 May 10;288(19):13305-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory