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Fbxw10 Gene Detail
Summary
  • Symbol
    Fbxw10
  • Name
    F-box and WD-40 domain protein 10
  • Synonyms
    Fbw10, SM25H2, SM2SH2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3052463
    NCBI Gene: 213980
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:62847069-62877465 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30397 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 38.78 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CDRT1, CMT1A duplicated region transcript 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CDRT1, CMT1A duplicated region transcript 1
    Orthology source: HGNC
  • Synonyms
    C170RF1, C17ORF1, C17ORF1A, FBXW10B, FBXW10P1, HREP, SM25H2
  • Links
    NCBI Gene ID: 374286
    neXtProt AC: NX_O95170
    UniProt: O95170

  • Chr Location
    17p12; chr17:15565482-15619704 (-)  GRCh38.p7

  • Human Ortholog
    FBXW10, F-box and WD repeat domain containing 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Fbw10, HREP, SM25H2, SM2SH2
  • Links
    NCBI Gene ID: 10517
    neXtProt AC: NX_Q5XX13
    UniProt: Q5XX13

  • Chr Location
    17p11.2; chr17:18744013-18779349 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005877 VEGA Gene Model | MGI Sequence Detail 30397 C57BL/6J ±  kb
transcript OTTMUST00000013089 VEGA | MGI Sequence Detail 3354 Not Applicable  
polypeptide OTTMUSP00000006077 VEGA | MGI Sequence Detail 1030 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    270 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory