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Fbxw10 Gene Detail
Summary
  • Symbol
    Fbxw10
  • Name
    F-box and WD-40 domain protein 10
  • Synonyms
    Fbw10, SM25H2, SM2SH2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3052463
    NCBI Gene: 213980
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:62847069-62877465 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 38.78 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3052463
protein coding gene Chr11:62847067-62877465 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018464
protein coding gene Chr11:62936355-62971827 (+)
A/J MGP_AJ_G0018433
protein coding gene Chr11:60593267-60627697 (+)
AKR/J MGP_AKRJ_G0018402
protein coding gene Chr11:62460691-62494280 (+)
BALB/cJ MGP_BALBcJ_G0018404
protein coding gene Chr11:60871527-60902383 (+)
C3H/HeJ MGP_C3HHeJ_G0018217
protein coding gene Chr11:62435978-62467134 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018856
protein coding gene Chr11:64901883-64936326 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016500
protein coding gene Chr11:57673345-57703781 (+)
CAST/EiJ MGP_CASTEiJ_G0017773
protein coding gene Chr11:62593822-62627596 (+)
CBA/J MGP_CBAJ_G0018191
protein coding gene Chr11:67696963-67736457 (+)
DBA/2J MGP_DBA2J_G0018300
protein coding gene Chr11:60145019-60176739 (+)
FVB/NJ MGP_FVBNJ_G0018290
protein coding gene Chr11:59813365-59843729 (+)
LP/J MGP_LPJ_G0018372
protein coding gene Chr11:63464636-63498695 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018314
protein coding gene Chr11:68684228-68717080 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018897
protein coding gene Chr11:62619346-62650475 (+)
PWK/PhJ MGP_PWKPhJ_G0017547
protein coding gene Chr11:60765011-60796803 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017337
protein coding gene Chr11:62468663-62504067 (+)
WSB/EiJ MGP_WSBEiJ_G0017826
protein coding gene Chr11:62236011-62269487 (+)



Homology
more
  • Human Ortholog
    CDRT1, CMT1A duplicated region transcript 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CDRT1, CMT1A duplicated region transcript 1
    Orthology source: HGNC
  • Synonyms
    C170RF1, C17ORF1, C17ORF1A, FBXW10B, FBXW10P1, HREP, SM25H2
  • Links
    NCBI Gene ID: 374286
    neXtProt AC: NX_O95170
    UniProt: O95170

  • Chr Location
    17p12; chr17:15565482-15619704 (-)  GRCh38.p7

  • Human Ortholog
    FBXW10, F-box and WD repeat domain containing 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Fbw10, HREP, SM25H2, SM2SH2
  • Links
    NCBI Gene ID: 10517
    neXtProt AC: NX_Q5XX13
    UniProt: Q5XX13

  • Chr Location
    17p11.2; chr17:18744013-18779349 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090173 Ensembl Gene Model | MGI Sequence Detail 30397 C57BL/6J ±  kb
transcript ENSMUST00000036085 Ensembl | MGI Sequence Detail 3354 Not Applicable  
polypeptide ENSMUSP00000046156 Ensembl | MGI Sequence Detail 1030 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR036047 F-box-like domain superfamily
    IPR020472 G-protein beta WD-40 repeat
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
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  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory