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Znhit3 Gene Detail
Summary
  • Symbol
    Znhit3
  • Name
    zinc finger, HIT type 3
  • Synonyms
    Trip3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3051596
    NCBI Gene: 448850
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:84801776-84807192 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3051596
 protein coding gene Chr11:84801776-84807192 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018876
 protein coding gene Chr11:86370891-86376307 (-)
A/J MGP_AJ_G0018843
 protein coding gene Chr11:83071839-83078868 (-)
AKR/J MGP_AKRJ_G0018813
 protein coding gene Chr11:85537309-85544695 (-)
BALB/cJ MGP_BALBcJ_G0018816
 protein coding gene Chr11:83462440-83468342 (-)
C3H/HeJ MGP_C3HHeJ_G0018630
 protein coding gene Chr11:85589660-85595654 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019268
 protein coding gene Chr11:88996003-89001373 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016901
 protein coding gene Chr11:80157590-80165147 (-)
CAST/EiJ MGP_CASTEiJ_G0018185
 protein coding gene Chr11:86222512-86227953 (-)
CBA/J MGP_CBAJ_G0018601
 protein coding gene Chr11:92770274-92781365 (-)
DBA/2J MGP_DBA2J_G0018709
 protein coding gene Chr11:82645547-82651730 (-)
FVB/NJ MGP_FVBNJ_G0018698
 protein coding gene Chr11:82136333-82142414 (-)
LP/J MGP_LPJ_G0018779
 protein coding gene Chr11:86891856-86897426 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018725
 protein coding gene Chr11:92904844-92910781 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019308
 protein coding gene Chr11:85810480-85816366 (-)
PWK/PhJ MGP_PWKPhJ_G0017954
 protein coding gene Chr11:83417171-83423355 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017746
 protein coding gene Chr11:85355831-85362724 (-)
WSB/EiJ MGP_WSBEiJ_G0018236
 protein coding gene Chr11:85647207-85653736 (-)



Homology
more
  • Human Ortholog
    ZNHIT3, zinc finger HIT-type containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNHIT3, zinc finger HIT-type containing 3
  • Synonyms
    Hit1, PEHO, TRIP3
  • Links
    NCBI Gene ID: 9326
    neXtProt AC: NX_Q15649
    UniProt: Q15649

  • Chr Location
    17q12; chr17:36486629-36499312 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ZNHIT3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    13
  • Targeted
    3
  • Genomic Mutations
    3 involving Znhit3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    13 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    5
  • cDNA Data
    78
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 448850 NCBI Gene Model | MGI Sequence Detail 5417 C57BL/6J ±  kb
transcript NM_001359182 RefSeq | MGI Sequence Detail 1108 C57BL/6  
polypeptide Q9CQK1 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 79
    cDNA 78
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:334297 Warren EB, et al., 17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasis. Dis Model Mech. 2022 Dec 1;15(12):dmm049752
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory