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Nup85 Gene Detail
Summary
  • Symbol
    Nup85
  • Name
    nucleoporin 85
  • Synonyms
    frount, Pcnt1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3046173
    NCBI Gene: 445007
  • Gene Overview
    MyGene.info: NUP85
Location & Maps
more
  • Sequence Map
    Chr11:115564434-115583985 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19552 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.87 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NUP85, nucleoporin 85
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP85, nucleoporin 85
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FROUNT, Nup75
  • Links
    NCBI Gene ID: 79902
    neXtProt AC: NX_Q9BW27

  • Chr Location
    17q25.1; chr17:75205450-75235759 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11755
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: NUP85
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    34
  • Gene trapped
    32
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003479 VEGA Gene Model | MGI Sequence Detail 19552 C57BL/6J ±  kb
transcript OTTMUST00000007443 VEGA | MGI Sequence Detail 2230 Not Applicable  
polypeptide OTTMUSP00000003583 VEGA | MGI Sequence Detail 656 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    143 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000011523 nuclear pore complex protein Nup85
  • InterPro Domains
    IPR011502 Nucleoporin Nup85-like
Molecular
Reagents
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  • All nucleic 122
    cDNA 122

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:224530 Dietrich JE, et al., Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep. 2015 Aug;16(8):1005-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory