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Lcn6 Gene Detail
Summary
  • Symbol
    Lcn6
  • Name
    lipocalin 6
  • Synonyms
    9230101D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045364
    NCBI Gene: 620709
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25676786-25681608 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 17.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045364
protein coding gene Chr2:25676631-25681608 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025464
protein coding gene Chr2:23590061-23594883 (+)
A/J MGP_AJ_G0025441
protein coding gene Chr2:22670915-22675737 (+)
AKR/J MGP_AKRJ_G0025411
protein coding gene Chr2:23429368-23434190 (+)
BALB/cJ MGP_BALBcJ_G0025437
protein coding gene Chr2:22786197-22791019 (+)
C3H/HeJ MGP_C3HHeJ_G0025198
protein coding gene Chr2:23365084-23369906 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025881
protein coding gene Chr2:24345378-24350200 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023292
protein coding gene Chr2:21577340-21582564 (+)
CAST/EiJ MGP_CASTEiJ_G0024661
protein coding gene Chr2:23232612-23237433 (+)
CBA/J MGP_CBAJ_G0025176
protein coding gene Chr2:25175960-25180782 (+)
DBA/2J MGP_DBA2J_G0025309
protein coding gene Chr2:22515539-22520361 (+)
FVB/NJ MGP_FVBNJ_G0025271
protein coding gene Chr2:22258157-22262979 (+)
LP/J MGP_LPJ_G0025395
protein coding gene Chr2:23524432-23529254 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025302
protein coding gene Chr2:25353576-25358398 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025940
protein coding gene Chr2:23387893-23392723 (+)
PWK/PhJ MGP_PWKPhJ_G0024409
protein coding gene Chr2:22324341-22329164 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024209
protein coding gene Chr2:23522054-23527086 (+)
WSB/EiJ MGP_WSBEiJ_G0024730
protein coding gene Chr2:23450368-23455198 (+)



Homology
more
  • Human Ortholog
    LCN6, lipocalin 6
  • Vertebrate Orthologs
    6
  • Human Ortholog
    LCN6, lipocalin 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hLcn5, LCN5, UNQ643
  • Links
    NCBI Gene ID: 158062
    neXtProt AC: NX_P62502
    UniProt: P62502

  • Chr Location
    9q34.3; chr9:136744017-136748528 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice with loss of expression in the testes show premature acrosome reaction and elevated intracellular calcium levels in sperm.
Gene Ontology
(GO)
Classifications
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Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045684 Ensembl Gene Model | MGI Sequence Detail 4823 C57BL/6J ±  kb
transcript ENSMUST00000114199 Ensembl | MGI Sequence Detail 729 Not Applicable  
polypeptide ENSMUSP00000109837 Ensembl | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Phenotypes 4
  • Earliest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
  • Latest
    J:256079 Yin Q, et al., Impaired sperm maturation in conditional Lcn6 knockout mice. Biol Reprod. 2018 Jan 1;98(1):28-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory