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Cpa6
Gene Detail
Symbol

Name
ID
Cpa6
carboxypeptidase A6
MGI:3045348
Synonyms
9030616D13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
2.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:10324720-10719945 bp, - strand
From VEGA annotation of GRCm38

  395226 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75130  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: carboxypeptidase
Gene Tree: Cpa6

Human
homologs
Human Homolog CPA6, carboxypeptidase A6
NCBI Gene ID 57094
neXtProt AC  NX_Q8N4T0
Human Synonyms  CPAH, ETL5, FEB11
Human Chr (Location)  8q13.2; chr8:67422170-67746385 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human CPA6
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cpa6 interacts with 212 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process proteolysis
Component extracellular region, proteinaceous extracellular matrix
Function carboxypeptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (64)    Tissues (35)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 49
RT-PCR 15
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000024232 (Evidence)
Ensembl Gene ModelENSMUSG00000042501 (Evidence)
Entrez Gene329093 (Evidence)
UniGene336423
DFCITC1591399, TC1596560
DoTSDT.91328154, DT.94137516
NIA Mouse Gene IndexU021123
EC3.4.17.-
Consensus CDS ProjectCCDS14819.1
International Mouse Knockout Project StatusCpa6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024232 VEGA Gene Model | MGI Sequence Detail 395226 C57BL/6J ±  kb
transcript OTTMUST00000059299 VEGA | MGI Sequence Detail 1932 Not Applicable 
polypeptide OTTMUSP00000028837 VEGA | MGI Sequence Detail 438 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(2494 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2508)
Protein-related
information
ResourceIDDescription
InterPro IPR000834 Peptidase M14, carboxypeptidase A
InterPro IPR003146 Proteinase inhibitor, carboxypeptidase propeptide
InterPro IPR009020 Proteinase inhibitor, propeptide
Protein Ontology PR:000005800 carboxypeptidase A6
References
(Earliest) J:99338 Fontenele-Neto JD, et al., Identification and distribution of mouse carboxypeptidase A-6. Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):132-42
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory