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Mettl24 Gene Detail
Summary
  • Symbol
    Mettl24
  • Name
    methyltransferase like 24
  • Synonyms
    9030224M15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045338
    NCBI Gene: 327747
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:40683282-40811083 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 22.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    840 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045338
protein coding gene Chr10:40682315-40811086 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017166
protein coding gene Chr10:39288167-39423748 (+)
A/J MGP_AJ_G0017143
protein coding gene Chr10:38194453-38328723 (+)
AKR/J MGP_AKRJ_G0017103
protein coding gene Chr10:38749327-38883822 (+)
BALB/cJ MGP_BALBcJ_G0017105
protein coding gene Chr10:38278370-38410883 (+)
C3H/HeJ MGP_C3HHeJ_G0016926
protein coding gene Chr10:39072144-39206858 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017564
protein coding gene Chr10:40500940-40638862 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015260
protein coding gene Chr10:36160743-36292139 (+)
CAST/EiJ MGP_CASTEiJ_G0016505
protein coding gene Chr10:39271718-39411537 (+)
CBA/J MGP_CBAJ_G0016900
protein coding gene Chr10:42330815-42487412 (+)
DBA/2J MGP_DBA2J_G0017005
protein coding gene Chr10:37715587-37843568 (+)
FVB/NJ MGP_FVBNJ_G0017000
protein coding gene Chr10:37207214-37339392 (+)
LP/J MGP_LPJ_G0017082
protein coding gene Chr10:39272442-39407240 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017030
protein coding gene Chr10:43167471-43305453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017601
protein coding gene Chr10:38727515-38863905 (+)
PWK/PhJ MGP_PWKPhJ_G0016285
protein coding gene Chr10:37595088-37731978 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016069
protein coding gene Chr10:38561697-38697665 (+)
WSB/EiJ MGP_WSBEiJ_G0016568
protein coding gene Chr10:39073186-39203643 (+)



Homology
more
  • Human Ortholog
    METTL24, methyltransferase like 24
  • Vertebrate Orthologs
    9
  • Human Ortholog
    METTL24, methyltransferase like 24
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf186
  • Links
    NCBI Gene ID: 728464
    neXtProt AC: NX_Q5JXM2
    UniProt: Q5JXM2

  • Chr Location
    6q21; chr6:110245946-110358272 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mettl24
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045555 Ensembl Gene Model | MGI Sequence Detail 127802 C57BL/6J ±  kb
transcript ENSMUST00000058747 Ensembl | MGI Sequence Detail 1529 Not Applicable  
polypeptide ENSMUSP00000049997 Ensembl | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory