About   Help   FAQ
Bpi Gene Detail
Summary
  • Symbol
    Bpi
  • Name
    bactericidal permeablility increasing protein
  • Synonyms
    9230105K17Rik, Bpifd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045315
    NCBI Gene: 329547
Location & Maps
more
  • Sequence Map
    Chr2:158258094-158284531 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26438 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 78.72 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    BPI, bactericidal/permeability-increasing protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BPI, bactericidal/permeability-increasing protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BPIFD1, rBPI
  • Links
    NCBI Gene ID: 671
    neXtProt AC: NX_P17213

  • Chr Location
    20q11.23; chr20:38304150-38337505 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    5
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015932 VEGA Gene Model | MGI Sequence Detail 26438 C57BL/6J ±  kb
transcript OTTMUST00000037849 VEGA | MGI Sequence Detail 1926 Not Applicable  
polypeptide OTTMUSP00000016993 VEGA | MGI Sequence Detail 486 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    183 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004794 bactericidal permeability-increasing protein
  • InterPro Domains
    IPR030181 Bactericidal permeability-increasing protein
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain
    IPR032942 BPI/LBP/Plunc family
    IPR030675 Lipid binding protein BPI/LBP
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:174122 Bingle CD, et al., Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Biochem Soc Trans. 2011 Aug 1;39(4):977-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory