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Zc3h12d Gene Detail
Summary
  • Symbol
    Zc3h12d
  • Name
    zinc finger CCCH type containing 12D
  • Synonyms
    D730019B10Rik, TFL
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045313
    NCBI Gene: 237256
Location & Maps
more
  • Sequence Map
    Chr10:7832470-7870397 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      37928 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 2.44 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ZC3H12D, zinc finger CCCH-type containing 12D
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZC3H12D, zinc finger CCCH-type containing 12D
    Orthology source: HomoloGene
  • Synonyms
    C6orf95, dJ281H8.1, MCPIP4, p34, TFL
  • Links
    NCBI Gene ID: 340152
    neXtProt AC: NX_A2A288

  • Chr Location
    chr6:149447630-149485012 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit disrupted regulation of excessive inflammation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039981 Ensembl Gene Model | MGI Sequence Detail 37928 C57BL/6J ±  kb
transcript ENSMUST00000039484 Ensembl | MGI Sequence Detail 4093 Not Applicable  
polypeptide ENSMUSP00000040217 Ensembl | MGI Sequence Detail 533 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    226 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:140125 Liang J, et al., Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation. PLoS One. 2008;3(8):e2880
  • Latest
    J:228445 Huang S, et al., Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation. J Biol Chem. 2015 Aug 21;290(34):20782-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory