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Garin5b Gene Detail
Summary
  • Symbol
    Garin5b
  • Name
    golgi associated RAB2 interactor family member 5B
  • Synonyms
    4930401F20Rik, Fam71e2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045311
    NCBI Gene: 243822
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4756225-4774301 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045311
 protein coding gene Chr7:4756225-4774362 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031559
 protein coding gene Chr7:1682226-1708644 (-)
A/J MGP_AJ_G0031533
 protein coding gene Chr7:1689702-1710704 (-)
AKR/J MGP_AKRJ_G0031462
 protein coding gene Chr7:1756676-1774591 (-)
BALB/cJ MGP_BALBcJ_G0031541
 protein coding gene Chr7:1729344-1750935 (-)
C3H/HeJ MGP_C3HHeJ_G0031262
 protein coding gene Chr7:1729772-1750398 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032002
 protein coding gene Chr7:1746393-1770431 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029126
 protein coding gene Chr7:1435533-1451826 (-)
CAST/EiJ MGP_CASTEiJ_G0030626
 protein coding gene Chr7:1673387-1694643 (-)
CBA/J MGP_CBAJ_G0031220
 protein coding gene Chr7:1945784-1966032 (-)
DBA/2J MGP_DBA2J_G0031379
 protein coding gene Chr7:1668038-1685490 (-)
FVB/NJ MGP_FVBNJ_G0031331
 protein coding gene Chr7:1634124-1652658 (-)
LP/J MGP_LPJ_G0031464
 protein coding gene Chr7:1790034-1812347 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031370
 protein coding gene Chr7:1881281-1905159 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032032
 protein coding gene Chr7:1668685-1692689 (-)
PWK/PhJ MGP_PWKPhJ_G0030354
 protein coding gene Chr7:1837179-1859479 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030179
 protein coding gene Chr7:1718250-1736694 (-)
WSB/EiJ MGP_WSBEiJ_G0030721
 protein coding gene Chr7:1685614-1706580 (-)



Homology
more
  • Human Ortholog
    GARIN5B, golgi associated RAB2 interactor family member 5B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GARIN5B, golgi associated RAB2 interactor family member 5B
  • Synonyms
    C19orf16, FAM71E2
  • Links
    NCBI Gene ID: 284418
    UniProt: Q8N5Q1

  • Chr Location
    19q13.42; chr19:55354908-55363260 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are subfertile, with impaired sperm motility, abnormal sperm head morphology, and impaired zona pellucida penetration during in vitro fertilization.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000092518 Ensembl Gene Model | MGI Sequence Detail 18077 C57BL/6J ±  kb
    transcript ENSMUST00000174409 Ensembl | MGI Sequence Detail 2716 Not Applicable  
    polypeptide ENSMUSP00000133885 Ensembl | MGI Sequence Detail 754 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR022168 Golgi associated RAB2 interactor protein-like, Rab2B-binding domain
    • GlyGen
      L7N480 1 site
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:6885580
    References
    more
    • Summaries
      All 17
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:350937 Wang H, et al., Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS Genet. 2024 Jun;20(6):e1011337
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory