Mamld1
Gene Detail

Symbol Name ID

Mamld1 mastermind-like domain containing 1 MGI:3045303

Synonyms

G630014P10Rik

Feature Type

protein coding gene

Genetic Map

Chromosome X

36.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

ChrX:71050256-71156056 bp, + strand From VEGA annotation of GRCm38   105801 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4010  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Mamld1

Human homologs

Human Homolog		MAMLD1, mastermind-like domain containing 1
NCBI Gene ID		10046
neXtProt AC		NX_Q13495
Human Synonyms		CG1, CXorf6, F18, HYSP2
Human Chr (Location)		Xq28; chrX:149531551-149682448 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MAMLD1

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Male mice exhibit normal male genitalia and fertility.

 

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, ...
Component	nucleus
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (94)    Tissues (8)    Images (24)
Theiler Stages: 23

Assay Type	Results
RNA in situ	94

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(14)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000017831 (Evidence)
Ensembl Gene Model	ENSMUSG00000059401 (Evidence)
Entrez Gene	333639 (Evidence)
UniGene	371730
DFCI	TC1612041
DoTS	DT.55279649
NIA Mouse Gene Index	U019911
Consensus CDS Project	CCDS57759.1, CCDS57760.1
International Mouse Knockout Project Status	Mamld1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017831	VEGA Gene Model | MGI Sequence Detail	105801	C57BL/6J
transcript	OTTMUST00000043173	VEGA | MGI Sequence Detail	4796	Not Applicable
polypeptide	OTTMUSP00000026854	VEGA | MGI Sequence Detail	803	Not Applicable

All sequences(27) RefSeq(4) UniProt(5)

Polymorphisms

SNPs(479 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026131	Mastermind-like domain-containing protein 1
Protein Ontology	PR:000032307	mastermind-like domain-containing protein 1

References

(Earliest) J:116501 Fukami M, et al., CXorf6 is a causative gene for hypospadias. Nat Genet. 2006 Dec;38(12):1369-71
(Latest) J:192626 Miyado M, et al., Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40
All references(24)