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Ankk1 Gene Detail
Summary
  • Symbol
    Ankk1
  • Name
    ankyrin repeat and kinase domain containing 1
  • Synonyms
    9930020N01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045301
    NCBI Gene: 244859
  • Gene Overview
    MyGene.info: ANKK1
Location & Maps
more
  • Sequence Map
    Chr9:49415222-49427021 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11800 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 26.83 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ANKK1, ankyrin repeat and kinase domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ANKK1, ankyrin repeat and kinase domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PKK2
  • Links
    NCBI Gene ID: 255239
    neXtProt AC: NX_Q8NFD2

  • Chr Location
    11q23.2; chr11:113386038-113400418 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032257 Ensembl Gene Model | MGI Sequence Detail 11800 C57BL/6J ±  kb
transcript ENSMUST00000034792 Ensembl | MGI Sequence Detail 2686 Not Applicable  
polypeptide ENSMUSP00000034792 Ensembl | MGI Sequence Detail 745 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    115 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029094 ankyrin repeat and protein kinase domain-containing protein 1
  • EC
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
    IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
Molecular
Reagents
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  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 2
  • Earliest
    J:160857 Hoenicka J, et al., The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine. Biol Psychiatry. 2010 Jan 1;67(1):3-11
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory