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Tlr13 Gene Detail
Summary
  • Symbol
    Tlr13
  • Name
    toll-like receptor 13
  • Synonyms
    LOC279572
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045213
    NCBI Gene: 279572
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:106143275-106160493 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 47.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045213
protein coding gene ChrX:106143204-106160493 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036003
protein coding gene ChrX:102931051-102952280 (+)
A/J MGP_AJ_G0035982
protein coding gene ChrX:102699424-102722421 (+)
AKR/J MGP_AKRJ_G0035901
protein coding gene ChrX:105990827-106009851 (+)
BALB/cJ MGP_BALBcJ_G0035972
protein coding gene ChrX:101539658-101557911 (+)
C3H/HeJ MGP_C3HHeJ_G0035679
protein coding gene ChrX:103364001-103382233 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036499
protein coding gene ChrX:105866884-105885397 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033327
protein coding gene ChrX:100169723-100186588 (+)
CAST/EiJ MGP_CASTEiJ_G0034966
protein coding gene ChrX:87513050-87531392 (+)
CBA/J MGP_CBAJ_G0035654
protein coding gene ChrX:109190801-109208742 (+)
DBA/2J MGP_DBA2J_G0035808
protein coding gene ChrX:101987710-102005004 (+)
FVB/NJ MGP_FVBNJ_G0035749
protein coding gene ChrX:101306541-101325214 (+)
LP/J MGP_LPJ_G0035901
protein coding gene ChrX:103898153-103917261 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035781
protein coding gene ChrX:113875435-113893863 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036525
protein coding gene ChrX:102562578-102581513 (+)
PWK/PhJ MGP_PWKPhJ_G0034662
protein coding gene ChrX:85041776-85059468 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034491
protein coding gene ChrX:88253838-88272605 (+)
WSB/EiJ MGP_WSBEiJ_G0035104
protein coding gene ChrX:101268884-101286366 (+)



Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Macrophages isolated from mice carrying an ENU-induced mutation respond normally to known TLR ligands and can contain various viral infections; however, mice carrying this allele have not been tested for immune responses in vivo.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 279572 NCBI Gene Model | MGI Sequence Detail 17219 C57BL/6J ±  kb
transcript NM_205820 RefSeq | MGI Sequence Detail 4014 C57BL/6  
polypeptide Q6R5N8 UniProt | EBI | MGI Sequence Detail 991 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
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MGI:2147911, MGI:2685559
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:88906 Tabeta K, et al., Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3516-21
  • Latest
    J:277634 Bussey KA, et al., Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection. J Virol. 2019 Feb 1;93(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory