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Tgm6
Gene Detail
Symbol

Name
ID
Tgm6
transglutaminase 6
MGI:3044321
Synonyms
TGM3L
Feature Type
protein coding gene
Genetic Map
Chromosome 2
63.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:130112416-130154232 bp, + strand
From VEGA annotation of GRCm38

  41817 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27970  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TGM6
Protein SuperFamily: TGM_EBP42
Gene Tree: Tgm6

Human
homologs
TGM6, transglutaminase 6
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 343641
neXtProt AC: NX_O95932

Human Synonyms: dJ734P14.3, SCA35, TG6, TGM3L, TGY

Human Chr (Location): 20p13; chr20:2380908-2432753 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TGM6

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Tgm6 interacts with 148 markers (Mir18, Mir18b, Mir26b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process biological_process
Component cytoplasm
Function protein-glutamine gamma-glutamyltransferase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tgm6    NEW 
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000015503 (Evidence)
Ensembl Gene Model ENSMUSG00000027403 (Evidence)
Entrez Gene 241636 (Evidence)
UniGene 83437
DFCI TC1588543
DoTS DT.102520171, DT.91419737, DT.102550220, DT.94144034, DT.111153845
NIA Mouse Gene Index U002467
EC 2.3.2.13
Consensus CDS Project CCDS16734.1
International Mouse Phenotyping Consortium Status Tgm6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015503 VEGA Gene Model | MGI Sequence Detail 41817 C57BL/6J ±  kb
transcript OTTMUST00000036815 VEGA | MGI Sequence Detail 3327 Not Applicable 
polypeptide OTTMUSP00000016517 VEGA | MGI Sequence Detail 706 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(499 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR023608 Protein-glutamine gamma-glutamyltransferase, eukaryota
InterPro IPR013808 Transglutaminase, conserved site
InterPro IPR008958 Transglutaminase, C-terminal
InterPro IPR002931 Transglutaminase-like
InterPro IPR001102 Transglutaminase, N-terminal
Protein Ontology PR:000016297 protein-glutamine gamma-glutamyltransferase 6
References
(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:213110 Fukui M, et al., Identification of a highly reactive substrate peptide for transglutaminase 6 and its use in detecting transglutaminase activity in the skin epidermis. FEBS J. 2013 Mar;280(6):1420-9
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory