Tgm6
Gene Detail

Symbol Name ID

Tgm6 transglutaminase 6 MGI:3044321

Synonyms

TGM3L

Feature Type

protein coding gene

Genetic Map

Chromosome 2

63.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr2:130112416-130154232 bp, + strand From VEGA annotation of GRCm38   41817 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:27970  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: TGM_EBP42
Gene Tree: Tgm6

Human homologs

Human Homolog		TGM6, transglutaminase 6
NCBI Gene ID		343641
neXtProt AC		NX_O95932
Human Synonyms		dJ734P14.3, SCA35, TG6, TGM3L, TGY
Human Chr (Location)		20p13; chr20:2361554-2413399 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TGM6

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	biological_process
Component	cellular_component
Function	metal ion binding, protein-glutamine gamma-glutamyltransferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000015503 (Evidence)
Ensembl Gene Model	ENSMUSG00000027403 (Evidence)
Entrez Gene	241636 (Evidence)
UniGene	83437
DFCI	TC1588543
DoTS	DT.102520171, DT.102550220, DT.111153845, DT.91419737
NIA Mouse Gene Index	U002467
EC	2.3.2.13
Consensus CDS Project	CCDS16734.1
International Mouse Knockout Project Status	Tgm6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015503	VEGA Gene Model | MGI Sequence Detail	41817	C57BL/6J
transcript	OTTMUST00000036815	VEGA | MGI Sequence Detail	3327	Not Applicable
polypeptide	OTTMUSP00000016517	VEGA | MGI Sequence Detail	706	Not Applicable

All sequences(30) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(234 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014756	Immunoglobulin E-set
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR023608	Protein-glutamine gamma-glutamyltransferase, eukaryota
InterPro	IPR013808	Transglutaminase, conserved site
InterPro	IPR008958	Transglutaminase, C-terminal
InterPro	IPR002931	Transglutaminase-like
InterPro	IPR001102	Transglutaminase, N-terminal
Protein Ontology	PR:000016297	protein-glutamine gamma-glutamyltransferase 6

References

(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:193871 Guan WJ, et al., Spinocerebellar ataxia type 35 (SCA35)-associated transglutaminase 6 mutants sensitize cells to apoptosis. Biochem Biophys Res Commun. 2013 Jan 11;430(2):780-6
All references(27)