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Neurl2
Gene Detail
 Symbol
Name
ID
Neurl2
neuralized-like 2 (Drosophila)
MGI:3043305
Synonyms Ozz, Ozz-E3
Feature Type protein coding gene
Genetic Map
Chromosome 2
85.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:164830732-164833456 bp, - strand
From VEGA annotation of GRCm38

  2725 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15435  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Neurl2

Human
homologs
Human Homolog NEURL2, neuralized E3 ubiquitin protein ligase 2
NCBI Gene ID 140825
neXtProt AC  NX_Q9BR09
Human Synonyms  C20orf163, OZZ, OZZ-E3
Human Chr (Location)  20q13.12; chr20:45888472-45891287 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) Targeted(4)
 
Homozygous null mice display myofiber abnormalities in skeletal muscle and decreased body weight.
 
Interactions
Neurl2 interacts with 14 markers (Mir34b, Mir34c, Mir325, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process intracellular signal transduction, myofibril assembly, ...
Component cytoplasm, muscle tendon junction, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(2) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001109 (Evidence)
Ensembl Gene ModelENSMUSG00000039873 (Evidence)
Entrez Gene415115 (Evidence)
DFCITC1585304
NIA Mouse Gene IndexU023649
Consensus CDS ProjectCCDS38330.1
International Mouse Knockout Project StatusNeurl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001109 VEGA Gene Model | MGI Sequence Detail 2725 C57BL/6J ±  kb
transcript OTTMUST00000002175 VEGA | MGI Sequence Detail 1014 Not Applicable 
polypeptide OTTMUSP00000001062 VEGA | MGI Sequence Detail 285 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006573 NEUZ
InterPro IPR001496 SOCS protein, C-terminal
Protein Ontology PR:000011150 neuralized-like protein 2
References (Earliest) J:40589 Rottier RJ, et al., Identification of the promoters for the human and murine protective protein/cathepsin A genes. DNA Cell Biol. 1997 May;16(5):599-610
(Latest) J:158726 Campos Y, et al., Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory