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Itprip
Gene Detail
Symbol

Name
ID
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
MGI:3042776
Synonyms
DANGER
Feature Type
protein coding gene
Genetic Map
Chromosome 19
40.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:47894598-47919299 bp, - strand
From Ensembl annotation of GRCm38

  24702 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62157  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Itprip

Human
homologs
Human Homolog ITPRIP, inositol 1,4,5-trisphosphate receptor interacting protein
NCBI Gene ID 85450
neXtProt AC  NX_Q8IWB1
Human Synonyms  bA127L20, bA127L20.2, DANGER, KIAA1754
Human Chr (Location)  10q25.1; chr10:104309696-104338493 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for a null mutation are grossly normal, but MEF and neuronal cells show increased susceptibility to induced cell death due to increase in death-associated protein kinase (DAPK) activity.
 
Interactions
Itprip interacts with 236 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
cDNA source data(11)
External Resources: Allen Institute   GEO  
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000079254 (Evidence)
Entrez Gene414801 (Evidence)
DFCITC1576303, TC1630904, TC1644910
DoTSDT.101341754, DT.102556689, DT.55231454, DT.99851521
Consensus CDS ProjectCCDS29895.1
International Mouse Knockout Project StatusItprip
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079254 Ensembl Gene Model | MGI Sequence Detail 24702 C57BL/6J ±  kb
transcript ENSMUST00000095998 Ensembl | MGI Sequence Detail 3764 Not Applicable 
polypeptide ENSMUSP00000093697 Ensembl | MGI Sequence Detail 555 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(256 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024797 Inositol 1,4,5-triphosphate receptor-interacting protein
InterPro IPR026250 Inositol 1,4,5-trisphosphate receptor-interacting protein
InterPro IPR024810 Mab-21 domain
Protein Ontology PR:000009161 inositol 1,4,5-trisphosphate receptor-interacting protein
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory