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Tcaf3 Gene Detail
Summary
  • Symbol
    Tcaf3
  • Name
    TRPM8 channel-associated factor 3
  • Synonyms
    Eapa2, Fam115e
  • Feature Type
    protein coding gene
  • IDs
    MGI:3042585
    NCBI Gene: 403088
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:42587213-42597372 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 20.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3042585
protein coding gene Chr6:42584866-42597692 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030657
protein coding gene Chr6:41111517-41124130 (-)
A/J MGP_AJ_G0030630
protein coding gene Chr6:39313962-39327050 (-)
AKR/J MGP_AKRJ_G0030555
protein coding gene Chr6:40573296-40586446 (-)
BALB/cJ MGP_BALBcJ_G0030640
protein coding gene Chr6:39571196-39583983 (-)
C3H/HeJ MGP_C3HHeJ_G0030353
protein coding gene Chr6:40615259-40629163 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031094
protein coding gene Chr6:42137725-42150453 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028301
protein coding gene Chr6:37190724-37202944 (-)
CAST/EiJ MGP_CASTEiJ_G0029757
protein coding gene Chr6:40458900-40471638 (-)
CBA/J MGP_CBAJ_G0030328
protein coding gene Chr6:43852563-43865307 (-)
DBA/2J MGP_DBA2J_G0030473
protein coding gene Chr6:39162938-39175775 (-)
FVB/NJ MGP_FVBNJ_G0030429
protein coding gene Chr6:38913830-38926492 (-)
LP/J MGP_LPJ_G0030561
protein coding gene Chr6:41089257-41102444 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030463
protein coding gene Chr6:46113877-46126627 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031124
protein coding gene Chr6:40549788-40563401 (-)
PWK/PhJ MGP_PWKPhJ_G0029469
protein coding gene Chr6:38728983-38742178 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029305
protein coding gene Chr6:40110694-40123372 (-)
WSB/EiJ MGP_WSBEiJ_G0029833
protein coding gene Chr6:40552457-40566023 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 403088 NCBI Gene Model | MGI Sequence Detail 10160 C57BL/6J ±  kb
transcript NM_203396 RefSeq | MGI Sequence Detail 3110 C57BL/6  
polypeptide Q6QR59 UniProt | EBI | MGI Sequence Detail 914 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:124439 Setiady YY, et al., Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells. Blood. 2006 Feb 1;107(3):1056-62
  • Latest
    J:258941 Leonard JD, et al., Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen. Immunity. 2017 Jul 18;47(1):107-117.e8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory