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Nsfl1c
Gene Detail
Symbol

Name
ID
Nsfl1c
NSFL1 (p97) cofactor (p47)
MGI:3042273
Synonyms
MGC:61403, p47
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:151494182-151511414 bp, + strand
From VEGA annotation of GRCm38

  17233 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41114  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

HCOP human homology predictions: NSFL1C
Gene Tree: Nsfl1c

Human
homologs
NSFL1C, NSFL1 (p97) cofactor (p47)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 55968
neXtProt AC: NX_Q9UNZ2

Human Synonyms: dJ776F14.1, P47, UBX1, UBXD10, UBXN2C

Human Chr (Location): 20p13; chr20:1442162-1467720 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(10) Targeted(2)
Incidental mutations (data from CvDC )
Interactions
Nsfl1c interacts with 58 markers (Mir7-1, Mir20a, Mir27b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process autophagosome assembly, Golgi organization, ...
Component chromosome, cytoplasm, ...
Function ATPase binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (29)    Tissues (29)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 29
cDNA source data(137)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(139) cDNA(139)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000015798 (Evidence)
Ensembl Gene Model ENSMUSG00000027455 (Evidence)
Entrez Gene 386649 (Evidence)
UniGene 419479
DFCI TC1587917, TC1572633
DoTS DT.91413806, DT.87072776
NIA Mouse Gene Index U005569
Consensus CDS Project CCDS16868.1, CCDS71160.1
International Mouse Phenotyping Consortium Status Nsfl1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015798 VEGA Gene Model | MGI Sequence Detail 17233 C57BL/6J ±  kb
transcript OTTMUST00000037573 VEGA | MGI Sequence Detail 1486 Not Applicable 
polypeptide OTTMUSP00000016841 VEGA | MGI Sequence Detail 372 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)    SNPs within 2kb including multiple locations(109)
Protein-related
information
ResourceIDDescription
InterPro IPR012989 SEP domain
InterPro IPR009060 UBA-like
InterPro IPR001012 UBX
Protein Ontology PR:000011444 NSFL1 cofactor p47
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory