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Serpinb13 Gene Detail
Summary
  • Symbol
    Serpinb13
  • Name
    serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
  • Synonyms
    headpin, HUR7, HURPIN, PI13
  • Feature Type
    protein coding gene
  • IDs
    MGI:3042250
    NCBI Gene: 241196
  • Gene Overview
    MyGene.info: SERPINB13
Location & Maps
more
  • Sequence Map
    Chr1:106980984-107001195 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20212 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 50.34 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SERPINB13, serpin family B member 13
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SERPINB13, serpin family B member 13
    Orthology source: HomoloGene
  • Synonyms
    headpin, HSHUR7SEQ, HUR7, PI13
  • Links
    NCBI Gene ID: 5275
    neXtProt AC: NX_Q9UIV8

  • Chr Location
    18q21.33; chr18:63587202-63599199 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Serpinb13
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020999 VEGA Gene Model | MGI Sequence Detail 20212 C57BL/6J ±  kb
transcript OTTMUST00000049645 VEGA | MGI Sequence Detail 1607 Not Applicable  
polypeptide OTTMUSP00000023035 VEGA | MGI Sequence Detail 389 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    104 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 5
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:88342 Silverman GA, et al., Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci. 2004 Feb;61(3):301-25
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory