Serpinb13
Gene Detail

Symbol Name ID

Serpinb13 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13 MGI:3042250

Synonyms

headpin, HUR7, HURPIN, PI13

Feature Type

protein coding gene

Genetic Map

Chromosome 1

50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:106980984-107001195 bp, + strand From VEGA annotation of GRCm38   20212 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: serpin
Gene Tree: Serpinb13

Human homologs

Human Homolog		SERPINB13, serpin peptidase inhibitor, clade B (ovalbumin), member 13
NCBI Gene ID		5275
neXtProt AC		NX_Q9UIV8
Human Synonyms		headpin, HSHUR7SEQ, HUR7, PI13
Human Chr (Location)		18q21.33; chr18:61254534-61266433 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	cytoplasm, extracellular region
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) Genomic(5) cDNA(2)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000020999 (Evidence)
Ensembl Gene Model	ENSMUSG00000048775 (Evidence)
Entrez Gene	241196 (Evidence)
UniGene	110886
DFCI	TC1593850
DoTS	DT.87032333
NIA Mouse Gene Index	U055949
Consensus CDS Project	CCDS15213.1
International Mouse Knockout Project Status	Serpinb13

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020999	VEGA Gene Model | MGI Sequence Detail	20212	C57BL/6J
transcript	OTTMUST00000049645	VEGA | MGI Sequence Detail	1607	Not Applicable
polypeptide	OTTMUSP00000023035	VEGA | MGI Sequence Detail	389	Not Applicable

All sequences(21) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(82 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000014693	serpin B13

References

(Earliest) J:88342 Silverman GA, et al., Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci. 2004 Feb;61(3):301-25
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)