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Serpinb13
Gene Detail
Symbol

Name
ID
Serpinb13
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
MGI:3042250
Synonyms
headpin, HUR7, HURPIN, PI13
Feature Type
protein coding gene
Genetic Map
Chromosome 1
50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:106980984-107001195 bp, + strand
From VEGA annotation of GRCm38

  20212 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

HCOP human homology predictions: SERPINB13
Protein SuperFamily: serpin
Gene Tree: Serpinb13

Human
homologs
SERPINB13, serpin peptidase inhibitor, clade B (ovalbumin), member 13
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5275
neXtProt AC: NX_Q9UIV8

Human Synonyms: headpin, HSHUR7SEQ, HUR7, PI13

Human Chr (Location): 18q21.33; chr18:63587202-63599199 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb13 interacts with 131 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(5) cDNA(2)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000020999 (Evidence)
Ensembl Gene Model ENSMUSG00000048775 (Evidence)
Entrez Gene 241196 (Evidence)
UniGene 110886
DFCI TC1593850
DoTS DT.87032333
NIA Mouse Gene Index U055949
Consensus CDS Project CCDS15213.1
International Mouse Phenotyping Consortium Status Serpinb13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020999 VEGA Gene Model | MGI Sequence Detail 20212 C57BL/6J ±  kb
transcript OTTMUST00000049645 VEGA | MGI Sequence Detail 1607 Not Applicable 
polypeptide OTTMUSP00000023035 VEGA | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(104 from dbSNP Build 137)    SNPs within 2kb including multiple locations(106)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000014693 serpin B13
References
(Earliest) J:88342 Silverman GA, et al., Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci. 2004 Feb;61(3):301-25
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory