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Serpinb13
Gene Detail
 Symbol
Name
ID
Serpinb13
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
MGI:3042250
Synonyms headpin, HUR7, HURPIN, PI13
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:106980984-107001195 bp, + strand
From VEGA annotation of GRCm38

  20212 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: serpin
Gene Tree: Serpinb13

Human
homologs
Human Homolog SERPINB13, serpin peptidase inhibitor, clade B (ovalbumin), member 13
NCBI Gene ID 5275
neXtProt AC  NX_Q9UIV8
Human Synonyms  headpin, HSHUR7SEQ, HUR7, PI13
Human Chr (Location)  18q21.33; chr18:63587300-63599199 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb13 interacts with 132 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component cytoplasm, extracellular region, ...
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(5) cDNA(2)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000020999 (Evidence)
Ensembl Gene ModelENSMUSG00000048775 (Evidence)
Entrez Gene241196 (Evidence)
UniGene110886
DFCITC1593850
DoTSDT.87032333
NIA Mouse Gene IndexU055949
Consensus CDS ProjectCCDS15213.1
International Mouse Knockout Project StatusSerpinb13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020999 VEGA Gene Model | MGI Sequence Detail 20212 C57BL/6J ±  kb
transcript OTTMUST00000049645 VEGA | MGI Sequence Detail 1607 Not Applicable 
polypeptide OTTMUSP00000023035 VEGA | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(104 from dbSNP Build 137)    SNPs within 2kb including multiple locations(106)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000014693 serpin B13
References (Earliest) J:88342 Silverman GA, et al., Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci. 2004 Feb;61(3):301-25
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory