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Mettl25 Gene Detail
Summary
  • Symbol
    Mettl25
  • Name
    methyltransferase like 25
  • Synonyms
    BC067068
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041259
    NCBI Gene: 216292
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:105599050-105677241 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 55.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    305 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041259
protein coding gene Chr10:105599050-105677246 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017703
protein coding gene Chr10:107872337-107951835 (-)
A/J MGP_AJ_G0017680
protein coding gene Chr10:103874102-103946115 (-)
AKR/J MGP_AKRJ_G0017642
protein coding gene Chr10:106897844-106973694 (-)
BALB/cJ MGP_BALBcJ_G0017644
protein coding gene Chr10:104260911-104335428 (-)
C3H/HeJ MGP_C3HHeJ_G0017469
protein coding gene Chr10:106931831-107016716 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018101
protein coding gene Chr10:111630636-111718436 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015780
protein coding gene Chr10:98912808-98987194 (-)
CAST/EiJ MGP_CASTEiJ_G0017030
protein coding gene Chr10:107049130-107123316 (-)
CBA/J MGP_CBAJ_G0017438
protein coding gene Chr10:115942417-116024463 (-)
DBA/2J MGP_DBA2J_G0017543
protein coding gene Chr10:102973076-103053351 (-)
FVB/NJ MGP_FVBNJ_G0017537
protein coding gene Chr10:102046721-102127854 (-)
LP/J MGP_LPJ_G0017617
protein coding gene Chr10:108496505-108582310 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017567
protein coding gene Chr10:118228720-118317183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018139
protein coding gene Chr10:106860133-106936599 (-)
PWK/PhJ MGP_PWKPhJ_G0016812
protein coding gene Chr10:103055185-103130280 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016602
protein coding gene Chr10:105621931-105695802 (-)
WSB/EiJ MGP_WSBEiJ_G0017090
protein coding gene Chr10:106971761-107056557 (-)



Homology
more
  • Human Ortholog
    METTL25, methyltransferase like 25
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL25, methyltransferase like 25
  • Synonyms
    C12orf26
  • Links
    NCBI Gene ID: 84190
    neXtProt AC: NX_Q8N6Q8
    UniProt: Q8N6Q8

  • Chr Location
    12q21.31; chr12:82358528-82479239 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036009 Ensembl Gene Model | MGI Sequence Detail 78192 C57BL/6J ±  kb
    transcript ENSMUST00000046638 Ensembl | MGI Sequence Detail 2033 Not Applicable  
    polypeptide ENSMUSP00000038665 Ensembl | MGI Sequence Detail 597 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory