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Sema3g Gene Detail
Summary
  • Symbol
    Sema3g
  • Name
    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041242
    NCBI Gene: 218877
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30939830-30952309 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041242
 protein coding gene Chr14:30939817-30952309 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021123
 protein coding gene Chr14:24392844-24406398 (+)
A/J MGP_AJ_G0021071
 protein coding gene Chr14:23471545-23483894 (+)
AKR/J MGP_AKRJ_G0021048
 protein coding gene Chr14:24595525-24607888 (+)
BALB/cJ MGP_BALBcJ_G0021075
 protein coding gene Chr14:23593811-23608598 (+)
C3H/HeJ MGP_C3HHeJ_G0020858
 protein coding gene Chr14:24464926-24477275 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021507
 protein coding gene Chr14:25360963-25374139 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019070
 protein coding gene Chr14:23536602-23548914 (+)
CAST/EiJ MGP_CASTEiJ_G0020383
 protein coding gene Chr14:24228914-24241297 (+)
CBA/J MGP_CBAJ_G0020825
 protein coding gene Chr14:26334276-26346615 (+)
DBA/2J MGP_DBA2J_G0020947
 protein coding gene Chr14:23501417-23514011 (+)
FVB/NJ MGP_FVBNJ_G0020931
 protein coding gene Chr14:23464121-23476432 (+)
LP/J MGP_LPJ_G0021016
 protein coding gene Chr14:24718682-24731477 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020957
 protein coding gene Chr14:25598083-25610450 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021540
 protein coding gene Chr14:24356833-24369210 (+)
PWK/PhJ MGP_PWKPhJ_G0020131
 protein coding gene Chr14:22958759-22971855 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019955
 protein coding gene Chr14:23952526-23966364 (+)
WSB/EiJ MGP_WSBEiJ_G0020438
 protein coding gene Chr14:24419456-24431834 (+)



Homology
more
  • Human Ortholog
    SEMA3G, semaphorin 3G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SEMA3G, semaphorin 3G
  • Synonyms
    sem2
  • Links
    NCBI Gene ID: 56920
    neXtProt AC: NX_Q9NS98
    UniProt: Q9NS98

  • Chr Location
    3p21.1; chr3:52433035-52445103 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased lymphatic branching complexity with decreased lymphatic width.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    13
  • cDNA Data
    20
  • Literature Summary
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 218877 NCBI Gene Model | MGI Sequence Detail 12480 C57BL/6J ±  kb
    transcript NM_001025379 RefSeq | MGI Sequence Detail 3686 C57BL/6  
    polypeptide Q4LFA9 UniProt | EBI | MGI Sequence Detail 780 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 20
      Other 3

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 14
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:330969 Martins LF, et al., Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022 Oct 7;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory