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Ska3 Gene Detail
Summary
  • Symbol
    Ska3
  • Name
    spindle and kinetochore associated complex subunit 3
  • Synonyms
    F630043A04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041235
    NCBI Gene: 219114
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:57806561-57826185 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 30.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041235
protein coding gene Chr14:57806559-57826275 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021412
protein coding gene Chr14:52024868-52045568 (-)
A/J MGP_AJ_G0021373
protein coding gene Chr14:50976961-50996406 (-)
AKR/J MGP_AKRJ_G0021348
protein coding gene Chr14:52771172-52790768 (-)
BALB/cJ MGP_BALBcJ_G0021376
protein coding gene Chr14:50920699-50940290 (-)
C3H/HeJ MGP_C3HHeJ_G0021155
protein coding gene Chr14:52424380-52446458 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021815
protein coding gene Chr14:54577103-54599139 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019355
protein coding gene Chr14:49061797-49078415 (-)
CAST/EiJ MGP_CASTEiJ_G0020673
protein coding gene Chr14:48767022-48788324 (-)
CBA/J MGP_CBAJ_G0021122
protein coding gene Chr14:56203473-56225881 (-)
DBA/2J MGP_DBA2J_G0021243
protein coding gene Chr14:50651866-50671450 (-)
FVB/NJ MGP_FVBNJ_G0021224
protein coding gene Chr14:50044852-50064419 (-)
LP/J MGP_LPJ_G0021318
protein coding gene Chr14:53059470-53080102 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021252
protein coding gene Chr14:55540465-55561342 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021839
protein coding gene Chr14:51915953-51936506 (-)
PWK/PhJ MGP_PWKPhJ_G0020416
protein coding gene Chr14:47197368-47217706 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020249
protein coding gene Chr14:47999521-48021529 (-)
WSB/EiJ MGP_WSBEiJ_G0020725
protein coding gene Chr14:52235093-52254679 (-)



Homology
more
  • Human Ortholog
    SKA3, spindle and kinetochore associated complex subunit 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SKA3, spindle and kinetochore associated complex subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C13orf3, RAMA1
  • Links
    NCBI Gene ID: 221150
    neXtProt AC: NX_Q8IX90
    UniProt: Q8IX90

  • Chr Location
    13q12.11; chr13:21153595-21176602 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 124284
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SKA3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021965 Ensembl Gene Model | MGI Sequence Detail 19625 C57BL/6J ±  kb
transcript ENSMUST00000022536 Ensembl | MGI Sequence Detail 2260 Not Applicable  
polypeptide ENSMUSP00000022536 Ensembl | MGI Sequence Detail 411 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory