Ccdc157 Gene Detail

Summary

• Symbol
  Ccdc157
• Name
  coiled-coil domain containing 157
• Synonyms
  4930562D19Rik

• Feature Type
  protein coding gene
• IDs
  MGI:3041210
  NCBI Gene: 216516
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr11:4141123-4160293 bp, - strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 2.90 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  105 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3041210	protein coding gene	Chr11:4141123-4160293 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017976	protein coding gene	Chr11:1069075-1090306 (-)
A/J	MGP_AJ_G0017949	protein coding gene	Chr11:1084249-1103476 (-)
AKR/J	MGP_AKRJ_G0017913	protein coding gene	Chr11:1140090-1159175 (-)
BALB/cJ	MGP_BALBcJ_G0017917	protein coding gene	Chr11:1052865-1072644 (-)
C3H/HeJ	MGP_C3HHeJ_G0017730	protein coding gene	Chr11:1033057-1052151 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0018370	protein coding gene	Chr11:1154106-1173281 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016028	protein coding gene	Chr11:961761-981765 (-)
CAST/EiJ	MGP_CASTEiJ_G0017292	protein coding gene	Chr11:999499-1018446 (-)
CBA/J	MGP_CBAJ_G0017705	protein coding gene	Chr11:1391693-1414805 (-)
DBA/2J	MGP_DBA2J_G0017816	protein coding gene	Chr11:985362-1007182 (-)
FVB/NJ	MGP_FVBNJ_G0017807	protein coding gene	Chr11:1020127-1041108 (-)
LP/J	MGP_LPJ_G0017886	protein coding gene	Chr11:1177671-1197933 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017833	protein coding gene	Chr11:1065723-1085875 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018409	protein coding gene	Chr11:1141691-1165649 (-)
PWK/PhJ	MGP_PWKPhJ_G0017073	protein coding gene	Chr11:991069-1010704 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0016869	protein coding gene	Chr11:1093841-1114380 (-)
WSB/EiJ	MGP_WSBEiJ_G0017346	protein coding gene	Chr11:1009742-1030238 (-)

Homology

• Human Ortholog
  CCDC157, coiled-coil domain containing 157

• Vertebrate Orthologs
  10

• Human Ortholog
  CCDC157, coiled-coil domain containing 157
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:33854

  NCBI Gene ID: 550631

  neXtProt AC: NX_Q569K6

  UniProt: Q569K6

  
  
• Chr Location
  chr22:30356635-30378655 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 72271
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: CCDC157
• Gene Tree
  Ccdc157
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• Assay Results
  631
• cDNA Data
  34

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase ccdc157

Interactions

• Ccdc157 interacts with 258 markers (Mir1b, Mir7-1, Mir10a, ...) View All

Sequences &
Gene Models

• All Sequences
  64
• RefSeq
  24
• UniProt
  2
• CCDS
  CCDS24379.1, CCDS48743.1
• UniGene
  386854

• Ensembl
  ENSMUSG00000051427 (Evidence)
• NCBI Gene
  216516

Representative Sequences			Length	Strain/Species
genomic	216516	NCBI Gene Model | MGI Sequence Detail	19171	C57BL/6J
transcript	NM_177616	RefSeq | MGI Sequence Detail	5153	C57BL/6
polypeptide	Q5SPX1	UniProt | EBI | MGI Sequence Detail	718	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000030655 coiled-coil domain-containing protein 157
  (term hierarchy)
• InterPro Domains
  IPR029681 Coiled-coil domain-containing protein 157

Molecular
Reagents

• All nucleic 34

  cDNA 34

  
  

  Microarray probesets 3

References

• Summaries
  All 21

  Phenotypes 2
• Earliest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Ccdc157:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr106543	Chr11:4160286-4160305 (-)	-3 bp
Tssr106542	Chr11:4160232-4160282 (-)	36 bp
Tssr106541	Chr11:4160218-4160231 (-)	68 bp