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Iba57 Gene Detail
Summary
  • Symbol
    Iba57
  • Name
    IBA57 homolog, iron-sulfur cluster assembly
  • Synonyms
    4930543L23Rik, A230051G13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041174
    NCBI Gene: 216792
Location & Maps
more
  • Sequence Map
    Chr11:59155369-59163739 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8371 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 36.97 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    IBA57, IBA57 homolog, iron-sulfur cluster assembly
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IBA57, IBA57 homolog, iron-sulfur cluster assembly
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf69, MMDS3, SPG74
  • Links
    NCBI Gene ID: 200205
    neXtProt AC: NX_Q5T440

  • Chr Location
    1q42.13; chr1:228165728-228197905 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 13844
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IBA57
  • Gene Tree
Human Diseases
more
  • Diseases
    2 with human IBA57 associations

Human Disease Mouse Models
       Multiple Mitochondrial Dysfunctions Syndrome 3; MMDS3   OMIM: 615330
Spastic Paraplegia 74, Autosomal Recessive; SPG74   OMIM: 616451
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Iba57
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005782 VEGA Gene Model | MGI Sequence Detail 8371 C57BL/6J ±  kb
transcript OTTMUST00000012799 VEGA | MGI Sequence Detail 4021 Not Applicable  
polypeptide OTTMUSP00000005945 VEGA | MGI Sequence Detail 358 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    82 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 7

    Microarray probesets 6
Other
Accession IDs
less
MGI:1922421
References
more
  • Summaries
    All 24
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory