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Iba57
Gene Detail
Symbol

Name
ID
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
MGI:3041174
Synonyms
4930543L23Rik, A230051G13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
36.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:59155369-59163739 bp, - strand
From VEGA annotation of GRCm38

  8371 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13844  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IBA57
Gene Tree: Iba57

Human
homologs
IBA57, IBA57 homolog, iron-sulfur cluster assembly
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 200205
neXtProt AC: NX_Q5T440

Human Synonyms: C1orf69, MMDS3, SPG74

Human Chr (Location): 1q42.13; chr1:228165728-228197905 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human IBA57

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
Interactions
Iba57 interacts with 263 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process heme biosynthetic process, iron-sulfur cluster assembly
Component mitochondrial matrix, mitochondrion
Function poly(A) RNA binding, transferase activity
External Resources: FuncBase
Expression
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase iba57 ; ZFIN iba57    NEW 
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(7)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000005782 (Evidence)
Ensembl Gene Model ENSMUSG00000049287 (Evidence)
Entrez Gene 216792 (Evidence)
DFCI TC1583766, TC1592624, TC1674900, TC1719305
DoTS DT.101711333, DT.101725040, DT.97398235
NIA Mouse Gene Index U032835, U260788
EC 2.1.-.-
Consensus CDS Project CCDS24758.1
International Mouse Phenotyping Consortium Status Iba57
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005782 VEGA Gene Model | MGI Sequence Detail 8371 C57BL/6J ±  kb
transcript OTTMUST00000012799 VEGA | MGI Sequence Detail 4021 Not Applicable 
polypeptide OTTMUSP00000005945 VEGA | MGI Sequence Detail 358 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(9) UniProt(4)
Polymorphisms
SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013977 Glycine cleavage T-protein, C-terminal barrel domain
InterPro IPR006222 Glycine cleavage T-protein-like, N-terminal
InterPro IPR017703 YgfZ/GcvT conserved site
Protein Ontology PR:000030585 transferase CAF17, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:1922421

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory