About   Help   FAQ
Tnip3 Gene Detail
Summary
  • Symbol
    Tnip3
  • Name
    TNFAIP3 interacting protein 3
  • Synonyms
    9030611K07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041165
    NCBI Gene: 414084
Location & Maps
more
  • Sequence Map
    Chr6:65590398-65634040 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      43643 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 30.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TNIP3, TNFAIP3 interacting protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TNIP3, TNFAIP3 interacting protein 3
    Orthology source: HomoloGene
  • Synonyms
    ABIN-3, LIND
  • Links
    NCBI Gene ID: 79931
    neXtProt AC: NX_Q96KP6

  • Chr Location
    4q27; chr4:121131408-121227609 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Mice homozygous for a knock-out allele are viable and fertile and do not develop spontaneous inflammatory or autoimmune disease; mutant macrophages exhibit normal responses to IL-10 and LPS.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016677 VEGA Gene Model | MGI Sequence Detail 43643 C57BL/6J ±  kb
transcript OTTMUST00000040385 VEGA | MGI Sequence Detail 3769 Not Applicable  
polypeptide OTTMUSP00000018044 VEGA | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    517 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR033574 TNFAIP3-interacting protein 3
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:122758 Weaver BK, et al., ABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions. Mol Cell Biol. 2007 Jul;27(13):4603-16
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/23/2016
MGI 6.05
The Jackson Laboratory