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Iqub
Gene Detail
Symbol

Name
ID
Iqub
IQ motif and ubiquitin domain containing
MGI:3041159
Synonyms
4932408B21Rik, Trs4
Feature Type
protein coding gene
Genetic Map
Chromosome 6
11.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:24444865-24515067 bp, - strand
From VEGA annotation of GRCm38

  70203 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44790  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IQUB
Gene Tree: Iqub

Human
homologs
IQUB, IQ motif and ubiquitin domain containing
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 154865
neXtProt AC: NX_Q8NA54

Human Chr (Location): 7q31.32; chr7:123452181-123534664 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Iqub interacts with 250 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process cell projection organization, cilium morphogenesis, ...
Component acrosomal vesicle, motile cilium
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase iqub    NEW 
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000026862 (Evidence)
Ensembl Gene Model ENSMUSG00000046192 (Evidence)
Entrez Gene 214704 (Evidence)
UniGene 61131
DFCI TC1584011
DoTS DT.97350799
NIA Mouse Gene Index U027085
Consensus CDS Project CCDS19941.1
International Mouse Phenotyping Consortium Status Iqub
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026862 VEGA Gene Model | MGI Sequence Detail 70203 C57BL/6J ±  kb
transcript OTTMUST00000066421 VEGA | MGI Sequence Detail 3651 Not Applicable 
polypeptide OTTMUSP00000033288 VEGA | MGI Sequence Detail 788 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(335 from dbSNP Build 137)    SNPs within 2kb including multiple locations(337)
Protein-related
information
ResourceIDDescription
InterPro IPR000048 IQ motif, EF-hand binding site
InterPro IPR029071 Ubiquitin-related domain
Protein Ontology PR:000031633 IQ and ubiquitin-like domain-containing protein
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:182871 Lai CK, et al., Functional characterization of putative cilia genes by high-content analysis. Mol Biol Cell. 2011 Apr;22(7):1104-19
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory