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Zscan10 Gene Detail
Summary
  • Symbol
    Zscan10
  • Name
    zinc finger and SCAN domain containing 10
  • Synonyms
    Zfp206, Zscan10
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040700
    NCBI Gene: 332221
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:23819830-23829993 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 11.79 cM, cytoband A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040700
protein coding gene Chr17:23819800-23829993 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023258
protein coding gene Chr17:22501843-22514470 (+)
A/J MGP_AJ_G0023218
protein coding gene Chr17:21862500-21872618 (+)
AKR/J MGP_AKRJ_G0023188
protein coding gene Chr17:21932928-21945891 (+)
BALB/cJ MGP_BALBcJ_G0023223
protein coding gene Chr17:22076458-22086732 (+)
C3H/HeJ MGP_C3HHeJ_G0022983
protein coding gene Chr17:22294839-22308777 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023666
protein coding gene Chr17:23486036-23500897 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021147
protein coding gene Chr17:19435722-19446392 (+)
CAST/EiJ MGP_CASTEiJ_G0022489
protein coding gene Chr17:22126274-22138376 (+)
CBA/J MGP_CBAJ_G0022959
protein coding gene Chr17:24274077-24289817 (+)
DBA/2J MGP_DBA2J_G0023091
protein coding gene Chr17:21491468-21501846 (+)
FVB/NJ MGP_FVBNJ_G0023058
protein coding gene Chr17:21215739-21225581 (+)
LP/J MGP_LPJ_G0023165
protein coding gene Chr17:22762214-22772391 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023077
protein coding gene Chr17:24060238-24072198 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023705
protein coding gene Chr17:22226142-22237814 (+)
PWK/PhJ MGP_PWKPhJ_G0022237
protein coding gene Chr17:20278506-20289031 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022057
protein coding gene Chr17:20250564-20262099 (+)
WSB/EiJ MGP_WSBEiJ_G0022552
protein coding gene Chr17:22281599-22293294 (+)



Homology
more
  • Human Ortholog
    ZSCAN10, zinc finger and SCAN domain containing 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZSCAN10, zinc finger and SCAN domain containing 10
  • Synonyms
    ZFP206, ZNF206
  • Links
    NCBI Gene ID: 84891
    neXtProt AC: NX_Q96SZ4
    UniProt: Q96SZ4

  • Chr Location
    16p13.3; chr16:3088890-3099295 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    44 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit a pleiotropic phenotype including reduced weight, mild hypoplasia in the spleen, heart and long bones, eye malformations including microphthalmia, altered platelet counts, an activated immune status, and behavioral alterations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000023902 Ensembl Gene Model | MGI Sequence Detail 10164 C57BL/6J ±  kb
    transcript ENSMUST00000095595 Ensembl | MGI Sequence Detail 2698 Not Applicable  
    polypeptide ENSMUSP00000093255 Ensembl | MGI Sequence Detail 782 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 31
      Primer pair 5
      Other 2

      Microarray probesets 1
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 5
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory