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Zfp458
Gene Detail
Symbol

Name
ID
Zfp458
zinc finger protein 458
MGI:3040691
Synonyms
Rslcan-7
Feature Type
protein coding gene
Genetic Map
Chromosome 13
34.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:67254918-67269068 bp, - strand
From NCBI annotation of GRCm38

  14151 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128170  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque

HCOP human homology predictions: ZNF43
Gene Tree: Zfp458

Human
homologs
ZNF43, zinc finger protein 43
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 7594
neXtProt AC: NX_P17038

Human Synonyms: HTF6, KOX27, ZNF39L1

Human Chr (Location): 19p13.1-p12; chr19:21804949-21852068 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Zfp458 interacts with 196 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process regulation of transcription, DNA-templated
Component intracellular
Function metal ion binding, nucleic acid binding
External Resources: FuncBase
Expression
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000055480 (Evidence)
Entrez Gene 238690 (Evidence)
UniGene 306358
DFCI TC1587999
DoTS DT.110960234, DT.110960228, DT.55199804
Consensus CDS Project CCDS36710.1
International Mouse Phenotyping Consortium Status Zfp458
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 238690 NCBI Gene Model | MGI Sequence Detail 14151 C57BL/6J ±  kb
transcript NM_001001152 RefSeq | MGI Sequence Detail 3488 C57BL/6 
polypeptide Q6P5C7 UniProt | EBI | MGI Sequence Detail 752 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(220 from dbSNP Build 137)    SNPs within 2kb including multiple locations(226)
Protein-related
information
ResourceIDDescription
InterPro IPR001909 Krueppel-associated box
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Graphical View of Protein Domain Structure
References
(Earliest) J:86324 Krebs CJ, et al., Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 2003 Nov 1;17(21):2664-74
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
All references(19)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory