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Zfp708 Gene Detail
Summary
  • Symbol
    Zfp708
  • Name
    zinc finger protein 708
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040674
    NCBI Gene: 432769
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:67217463-67246040 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 34.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    376 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040674
protein coding gene Chr13:67217462-67246040 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020696
protein coding gene Chr13:67170700-67183065 (-)
A/J MGP_AJ_G0020652
protein coding gene Chr13:64722855-64734125 (-)
AKR/J MGP_AKRJ_G0020627
protein coding gene Chr13:66872424-66886721 (-)
BALB/cJ MGP_BALBcJ_G0020649
protein coding gene Chr13:65206995-65220091 (-)
C3H/HeJ MGP_C3HHeJ_G0020444
protein coding gene Chr13:66492209-66504260 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021086
protein coding gene Chr13:69524320-69535608 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018657
protein coding gene Chr13:62379028-62388917 (-)
CAST/EiJ MGP_CASTEiJ_G0019960
protein coding gene Chr13:65703431-65719715 (-)
CBA/J MGP_CBAJ_G0020402
protein coding gene Chr13:71989733-72002163 (-)
DBA/2J MGP_DBA2J_G0020527
protein coding gene Chr13:64612860-64625046 (-)
FVB/NJ MGP_FVBNJ_G0020508
protein coding gene Chr13:63644735-63657726 (-)
LP/J MGP_LPJ_G0020602
protein coding gene Chr13:67413718-67428356 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020537
protein coding gene Chr13:70858244-70873704 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021127
protein coding gene Chr13:66152388-66163731 (-)
PWK/PhJ MGP_PWKPhJ_G0019716
protein coding gene Chr13:63594627-63606093 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019542
protein coding gene Chr13:63171353-63183697 (-)
WSB/EiJ MGP_WSBEiJ_G0020022
protein coding gene Chr13:66619017-66630337 (-)



Homology
more
  • Human Ortholog
    ZNF28, zinc finger protein 28
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF28, zinc finger protein 28
  • Synonyms
    KOX24
  • Links
    NCBI Gene ID: 7576
    neXtProt AC: NX_P17035
    UniProt: P17035

  • Chr Location
    19q13.41; chr19:52797408-52857600 (-)  GRCh38

  • Human Ortholog
    ZNF429, zinc finger protein 429
  • Links
    NCBI Gene ID: 353088
    neXtProt AC: NX_Q86V71
    UniProt: Q86V71

  • Chr Location
    19p12; chr19:21496682-21556270 (+)  GRCh38

  • Human Ortholog
    ZNF611, zinc finger protein 611
  • Links
    NCBI Gene ID: 81856
    neXtProt AC: NX_Q8N823
    UniProt: Q8N823

  • Chr Location
    19q13.41; chr19:52702813-52735073 (-)  GRCh38

  • Human Ortholog
    ZNF813, zinc finger protein 813
  • Links
    NCBI Gene ID: 126017
    neXtProt AC: NX_Q6ZN06
    UniProt: Q6ZN06

  • Chr Location
    19q13.42; chr19:53467733-53496255 (+)  GRCh38

  • Human Ortholog
    ZNF860, zinc finger protein 860
  • Links
    NCBI Gene ID: 344787
    neXtProt AC: NX_A6NHJ4
    UniProt: A6NHJ4

  • Chr Location
    3p23-p22.3; chr3:31981750-32006443 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Knockout affects maternal epigenetic methylation patterning of RMER19B endogenous retroviral elements in early embryos.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058883 Ensembl Gene Model | MGI Sequence Detail 28578 C57BL/6J ±  kb
transcript ENSMUST00000109743 Ensembl | MGI Sequence Detail 2536 Not Applicable  
polypeptide ENSMUSP00000105365 Ensembl | MGI Sequence Detail 541 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145359
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:284126 Seah MKY, et al., The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons. Development. 2019 Jul 10;146(19):dev170266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory