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Thoc2l Gene Detail
Summary
  • Symbol
    Thoc2l
  • Name
    THO complex subunit 2-like
  • Synonyms
    BC005561, Gm3179
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040669
    NCBI Gene: 100042165
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:104656216-104702073 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 50.68 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040669
protein coding gene Chr5:104656172-104702073 (+)
129S1/SvImJ MGP_129S1SvImJ_G0006728
lincRNA gene Chr5:106205600-106235781 (+)
A/J MGP_AJ_G0006722
lincRNA gene Chr5:102224200-102255592 (+)
AKR/J MGP_AKRJ_G0006692
lincRNA gene Chr5:105532264-105562014 (+)
BALB/cJ MGP_BALBcJ_G0006697
lincRNA gene Chr5:103284183-103316248 (+)
C3H/HeJ MGP_C3HHeJ_G0006643
lincRNA gene Chr5:105927672-105961876 (+)
C57BL/6NJ MGP_C57BL6NJ_G0006862
lincRNA gene Chr5:110561490-110591591 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006119
lincRNA gene Chr5:97329588-97345010 (+)
CAST/EiJ MGP_CASTEiJ_G0006566
lincRNA gene Chr5:104642331-104672800 (+)
CBA/J MGP_CBAJ_G0006624
lincRNA gene Chr5:114404178-114441834 (+)
DBA/2J MGP_DBA2J_G0006645
lincRNA gene Chr5:102434885-102450418 (+)
FVB/NJ MGP_FVBNJ_G0006669
lincRNA gene Chr5:101194973-101224716 (+)
LP/J MGP_LPJ_G0006729
lincRNA gene Chr5:106809764-106840552 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0006653
lincRNA gene Chr5:119311608-119345487 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0006864
lincRNA gene Chr5:105045973-105074620 (+)
PWK/PhJ MGP_PWKPhJ_G0006505
lincRNA gene Chr5:100864711-100893757 (+)
SPRET/EiJ MGP_SPRETEiJ_G0006411
lincRNA gene Chr5:102707139-102743249 (+)
WSB/EiJ MGP_WSBEiJ_G0006617
lincRNA gene Chr5:105437881-105469183 (+)



Homology
more
  • Human Ortholog
    THOC2, THO complex 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THOC2, THO complex 2
  • Synonyms
    CXorf3, dJ506G2.1, hTREX120, MRX12, MRX35, THO2, XLID12
  • Links
    NCBI Gene ID: 57187
    neXtProt AC: NX_Q8NI27
    UniProt: Q8NI27

  • Chr Location
    Xq25; chrX:123600561-123733054 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human THOC2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000097392 Ensembl Gene Model | MGI Sequence Detail 45858 C57BL/6J ±  kb
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR040007 THO complex subunit 2
    IPR032302 THO complex subunit 2, N-terminal domain
    IPR021418 THO complex, subunitTHOC2, C-terminal
    IPR021726 THO complex, subunitTHOC2, N-terminal
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140897, MGI:2442700, MGI:3781358
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory