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Smco4 Gene Detail
Summary
  • Symbol
    Smco4
  • Name
    single-pass membrane protein with coiled-coil domains 4
  • Synonyms
    BC017612
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039636
    NCBI Gene: 170748
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:15404728-15456556 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 4.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1647 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039636
 protein coding gene Chr9:15379736-15456556 (+)
129S1/SvImJ ENSMUSG00200043926
 protein coding gene Chr9:12306592-12358439 (+)
A/J ENSMUSG00195032347
 protein coding gene Chr9:12191887-12243738 (+)
AKR/J ENSMUSG00220026821
 protein coding gene Chr9:12169637-12221488 (+)
BALB/cJ ENSMUSG00180035435
 protein coding gene Chr9:12316223-12368074 (+)
C3H/HeJ ENSMUSG00175033149
 protein coding gene Chr9:12263080-12314923 (+)
C57BL/6NJ ENSMUSG00215020037
 protein coding gene Chr9:12257705-12309537 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031798
 protein coding gene Chr9:11692032-11731626 (+)
CAST/EiJ ENSTCUG00005026583
 protein coding gene Chr9:12301711-12353439 (+)
CBA/J ENSMUSG00210032837
 protein coding gene Chr9:12294268-12346115 (+)
DBA/2J ENSMUSG00185023481
 protein coding gene Chr9:12382783-12434631 (+)
FVB/NJ ENSMUSG00205041082
 protein coding gene Chr9:12364871-12416725 (+)
JF1/MsJ ENSUMUG00000016063
 protein coding gene Chr9:12388487-12440430 (+)
LP/J ENSMUSG00230041628
 protein coding gene Chr9:12804644-12856489 (+)
NOD/ShiLtJ ENSMUSG00190023125
 protein coding gene Chr9:12293257-12345106 (+)
NZO/HlLtJ ENSMUSG00225048651
 protein coding gene Chr9:12702223-12753698 (+)
PWK/PhJ ENSLUMG00010040484
 protein coding gene Chr9:12318766-12370721 (+)
SPRET/EiJ ENSMSPG00010019615
 protein coding gene Chr9:12516875-12568685 (+)
WSB/EiJ ENSIUOG00005037178
 protein coding gene Chr9:11969745-12021581 (+)



Homology
more
  • Human Ortholog
    SMCO4, single-pass membrane protein with coiled-coil domains 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMCO4, single-pass membrane protein with coiled-coil domains 4
  • Synonyms
    C11orf75, FN5
  • Links
    NCBI Gene ID: 56935
    UniProt: Q9NRQ5

  • Chr Location
    11q21; chr11:93478468-93553979 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    19
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058173 Ensembl Gene Model | MGI Sequence Detail 51829 C57BL/6J ±  kb
transcript ENSMUST00000215907 Ensembl | MGI Sequence Detail 994 Not Applicable  
polypeptide ENSMUSP00000150121 Ensembl | MGI Sequence Detail 59 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000060106 single-pass membrane and coiled-coil domain-containing protein 4
    (term hierarchy)
  • InterPro Domains
    IPR027960 Protein of unknown function DUF4519
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:76178 Kehrer-Sawatzki H, et al., Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts. Gene. 2000 Jun 13;251(1):63-71
  • Latest
    J:182258 Taher L, et al., Global gene expression analysis of murine limb development. PLoS One. 2011;6(12):e28358
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory