Zbtb24
Gene Detail

Symbol Name ID

Zbtb24 zinc finger and BTB domain containing 24 MGI:3039618

Synonyms

ZNF450

Feature Type

protein coding gene

Genetic Map

Chromosome 10

22.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:41450396-41465571 bp, + strand From Ensembl annotation of GRCm38   15176 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8870  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Zbtb24

Human homologs

Human Homolog		ZBTB24, zinc finger and BTB domain containing 24
NCBI Gene ID		9841
neXtProt AC		NX_O43167
Human Synonyms		BIF1, ICF2, PATZ2, ZNF450
Human Chr (Location)		6q21; chr6:109783719-109804440 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ZBTB24

Alleles and phenotypes

All alleles(10) : Targeted(2) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	regulation of transcription, DNA-dependent, transcription, DNA-dependent
Component	nucleus
Function	DNA binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (71)    Tissues (48)    Images (4)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 28

Assay Type	Results
RNA in situ	56
RT-PCR	15

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000019826 (Evidence)
Entrez Gene	268294 (Evidence)
NIA Mouse Gene Index	U011432, U170784
Consensus CDS Project	CCDS23804.1
International Mouse Knockout Project Status	Zbtb24

Sequences

Length	Strain/Species
genomic	ENSMUSG00000019826	Ensembl Gene Model | MGI Sequence Detail	15176	C57BL/6J
transcript	ENSMUST00000080771	Ensembl | MGI Sequence Detail	2828	Not Applicable
polypeptide	ENSMUSP00000079592	Ensembl | MGI Sequence Detail	710	Not Applicable

All sequences(31) RefSeq(7) UniProt(1)

Polymorphisms

SNPs(92 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017956	AT hook, DNA-binding motif
InterPro	IPR013069	BTB/POZ
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology	PR:000017570	zinc finger and BTB domain-containing protein 24

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:140465 Guo G, et al., Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
All references(25)