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Zbtb24
Gene Detail
 Symbol
Name
ID
Zbtb24
zinc finger and BTB domain containing 24
MGI:3039618
Synonyms ZNF450
Feature Type protein coding gene
Genetic Map
Chromosome 10
22.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:41450396-41465571 bp, + strand
From Ensembl annotation of GRCm38

  15176 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8870  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Zbtb24

Human
homologs
Human Homolog ZBTB24, zinc finger and BTB domain containing 24
NCBI Gene ID 9841
neXtProt AC  NX_O43167
Human Synonyms  BIF1, ICF2, PATZ2, ZNF450
Human Chr (Location)  6q21; chr6:109462516-109483237 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ZBTB24
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Zbtb24 interacts with 96 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process hematopoietic progenitor cell differentiation, regulation of transcription, DNA-templated, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (64)    Tissues (43)    Images (4)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 56
RT-PCR 8
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000019826 (Evidence)
Entrez Gene268294 (Evidence)
NIA Mouse Gene IndexU011432, U170784
Consensus CDS ProjectCCDS23804.1
International Mouse Knockout Project StatusZbtb24
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019826 Ensembl Gene Model | MGI Sequence Detail 15176 C57BL/6J ±  kb
transcript ENSMUST00000080771 Ensembl | MGI Sequence Detail 2828 Not Applicable 
polypeptide ENSMUSP00000079592 Ensembl | MGI Sequence Detail 710 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017956 AT hook, DNA-binding motif
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017570 zinc finger and BTB domain-containing protein 24
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory