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Pigu Gene Detail
Summary
  • Symbol
    Pigu
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class U
  • Synonyms
    5430426F17Rik, Cdc91l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039607
    NCBI Gene: 228812
  • Gene Overview
    MyGene.info: PIGU
Location & Maps
more
  • Sequence Map
    Chr2:155278243-155357430 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      79188 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 77.18 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PIGU, phosphatidylinositol glycan anchor biosynthesis class U
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PIGU, phosphatidylinositol glycan anchor biosynthesis class U
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDC91L1, GAB1
  • Links
    NCBI Gene ID: 128869
    neXtProt AC: NX_Q9H490

  • Chr Location
    20q11.22; chr20:34560542-34677285 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6553
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: PIGU
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Gene trapped
    5
  • Targeted
    2
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Other Mouse Links
  • Other Vertebrate Links
    Xenbase pigu
    ZFIN pigu
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016004 VEGA Gene Model | MGI Sequence Detail 79188 C57BL/6J ±  kb
transcript OTTMUST00000038109 VEGA | MGI Sequence Detail 1636 Not Applicable  
polypeptide OTTMUSP00000017087 VEGA | MGI Sequence Detail 435 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    730 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012708 phosphatidylinositol glycan anchor biosynthesis class U protein
  • InterPro Domains
    IPR009600 GPI transamidase subunit PIG-U
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918597
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory