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B3gnt6
Gene Detail
Symbol

Name
ID
B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
MGI:3039603
Synonyms
Core3, Core-3
Feature Type
protein coding gene
Genetic Map
Chromosome 7
53.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:98192415-98199475 bp, - strand
From NCBI annotation of GRCm38

  7061 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16339  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog

Gene Tree: B3gnt6

Human
homologs
Human Homolog B3GNT6, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
NCBI Gene ID 192134
neXtProt AC  NX_Q6ZMB0
Human Synonyms  B3Gn-T6, beta-1,3-Gn-T6, beta3Gn-T6, BGnT-6
Human Chr (Location)  11q13.4; chr11:77034341-77041973 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozgous for a knock-out allele exhibit increased permeability of the intestinal barrier, increased susceptibility to DSS-induced colitis and accelerated colorectal tumorigenesis in mice treated with AOM and DSS.
 
Interactions
B3gnt6 interacts with 145 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(5) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000074004 (Evidence)
Entrez Gene272411 (Evidence)
UniGene98333
DFCITC1605399
DoTSDT.101714648
NIA Mouse Gene IndexU056156
EC2.4.1.-
Consensus CDS ProjectCCDS40027.1
International Mouse Knockout Project StatusB3gnt6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 272411 NCBI Gene Model | MGI Sequence Detail 7061 C57BL/6J ±  kb
transcript NM_001081167 RefSeq | MGI Sequence Detail 2367 Not Specified 
polypeptide Q3USF0 UniProt | EBI | MGI Sequence Detail 391 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(118 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004596 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
Graphical View of Protein Domain Structure
References
(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:194674 Ahmed I, et al., Evidence of functional cross talk between the Notch and NF-kappaB pathways in nonneoplastic hyperproliferating colonic epithelium. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G356-70
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory